130103 20241125101135.0 doi 10.37201/req/115.2023 sideral 136493 ART-2023-136493 eng Moreno Guillén, Santiago Tuberculosis in Spain: an opinion paper 2023 Access copy available to the general public Unrestricted This document is the result of the deliberations of the Committee on Emerging Pathogens and COVID-19 of the Illustrious Official College of Physicians of Madrid (ICOMEM) regarding the current situation of tuberculosis, particularly in Spain. We have reviewed aspects such as the evolution of its incidence, the populations currently most exposed and the health care circuits for the care of these patients in Spain. We have also discussed latent tuberculosis, the reality of extrapulmonary disease in the XXI century and the means available in daily practice for the diagnosis of both latent and active forms. The contribution of molecular biology, which has changed the perspective of this disease, was another topic of discussion. The paper tries to put into perspective both the classical drugs and their resistance figures and the availability and indications of the new ones. In addition, the reality of direct observation in the administration of antituberculosis drugs has been discussed. All this revolution is making it possible to shorten the treatment time for tuberculosis, a subject that has also been reviewed. If everything is done well, the risk of relapse of tuberculosis is small but it exists. On the other hand, many special situations have been discussed in this paper, such as tuberculosis in pediatric age and tuberculosis as a cause for concern in surgery and intensive care. The status of the BCG vaccine and its present indications as well as the future of new vaccines to achieve the old dream of eradicating this disease have been discussed. Finally, the ethical and medicolegal implications of this disease are not a minor issue and our situation in this regard has been reviewed. info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 1.9 2023 PHARMACOLOGY & PHARMACY 231 / 354 = 0.653 2023 Q3 T2 MICROBIOLOGY 130 / 161 = 0.807 2023 Q4 T3 0.399 2023 Medicine (miscellaneous) 2023 Q3 Pharmacology 2023 Q3 Microbiology (medical) 2023 Q3 2.9 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Rodríguez-Artalejo, Fernando Ruiz-Galiana, Julián Cantón, Rafael De Lucas Ramos, Pilar García-Botella, Alejandra García-Lledó, Alberto Hernández-Sampelayo, Teresa Gómez-Pavón, Javier González del Castillo, Juan Martín-Delgado, Mari Cruz Martín Sánchez, Francisco Javier Martínez-Sellés, Manuel Molero García, José María Santiago, Begoña Caminero, José Antonio Barros, Carlos García de Viedma, Darío Martín, Carlos Universidad de Zaragoza (orcid)0000-0003-2993-5478 Bouza, Emilio 1011 630 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Microbiología 36, 6 (2023), 562-583 Rev. esp. quimioter. Revista española de quimioterapia 0214-3429 375254 http://zaguan.unizar.es/record/130103/files/texto_completo.pdf Versión publicada 2972284 http://zaguan.unizar.es/record/130103/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130103 articulos driver 2024-11-22-12:00:38 ARTICLE