000130111 001__ 130111 000130111 005__ 20240122171020.0 000130111 0247_ $$2doi$$a10.23866/BRNRev:2019-0026 000130111 0248_ $$2sideral$$a136507 000130111 037__ $$aART-2020-136507 000130111 041__ $$aspa 000130111 100__ $$aMarin, José M. 000130111 245__ $$aSleep Apnoea and Cancer: Is There a Relationship? 000130111 260__ $$c2020 000130111 5060_ $$aAccess copy available to the general public$$fUnrestricted 000130111 5203_ $$aIn recent decades, obstructive sleep apnoea (OSA) has come to represent a major public health problem due to its prevalence and its health consequences. Although the association between OSA and cardiovascular morbidity and mortality is well recognized, its role as a promoter for the development and extension of neoplasms is less known. In recent years, intensive research on the subject has been developed. Bench and animal studies demonstrate how sleep fragmentation and intermittent hypoxia, characteristic phenomena of OSA, are capable of inducing tumorigenesis in various organs and cell lines. However, clinical and population-based epidemiological studies are showing certain contradictory results. These topics are reviewed and discussed in this paper. 000130111 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FIS/PI18-01524$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI15-01940 000130111 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000130111 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000130111 700__ $$0(orcid)0000-0001-6724-5158$$aVicente, Eugenio$$uUniversidad de Zaragoza 000130111 700__ $$aMarin-Oto, Marta 000130111 7102_ $$11013$$2653$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Otorrinolaringología 000130111 773__ $$g6, 1 (2020), 22-35$$pBarc. respir. netw. rev.$$tBarcelona respiratory network reviews$$x2462-3172 000130111 8564_ $$s383342$$uhttps://zaguan.unizar.es/record/130111/files/texto_completo.pdf$$yVersión publicada 000130111 8564_ $$s1596453$$uhttps://zaguan.unizar.es/record/130111/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000130111 909CO $$ooai:zaguan.unizar.es:130111$$particulos$$pdriver 000130111 951__ $$a2024-01-22-15:27:29 000130111 980__ $$aARTICLE