000130195 001__ 130195
000130195 005__ 20241125101142.0
000130195 0247_ $$2doi$$a10.1016/j.jagp.2023.04.012
000130195 0248_ $$2sideral$$a134574
000130195 037__ $$aART-2023-134574
000130195 041__ $$aeng
000130195 100__ $$0(orcid)0000-0002-1252-2397$$aLobo, Elena$$uUniversidad de Zaragoza
000130195 245__ $$aSex Differences in Longitudinal Trajectories of Cognitive Aging in Zaragoza, Spain
000130195 260__ $$c2023
000130195 5060_ $$aAccess copy available to the general public$$fUnrestricted
000130195 5203_ $$aObjectives: The objective of this study was to document the longitudinal trajectories of cognitive aging in a sample of cognitively healthy subjects of 55 years or older. The following differences between men and women were hypothesized: 1) in the cognitive loss through aging, 2) in the distinct trajectories identified; and 3) in the predictors associated with the identified trajectories. Design and setting: A 4-wave, population-based study in Zaragoza, Spain (1994-2006). Participants: A total of 2,403 individuals aged 55+ years, cognitively healthy at baseline. Measurements: All participants had at least three measurements with the Mini-Mental State Examination (MMSE). Validated Spanish versions of international instruments were used for assessment. Random effects linear panel regression model for analyzing differences by sex in MMSE scores through aging were performed, and growth mixture models (GMM) applied independently for each sex for modeling the longitudinal cognitive trajectories. Results: Women showed lower mean MMSE scores in all phases and significantly higher loss in the MMSE from phases 2 to 3 and 3 to 4. The best fitting age-adjusted model of the cognitive trajectories was a 4-class GMM in men and a 3-class in women. Education was a predictor of cognitive trajectories in both men and women. Dependence on iADLs and alcohol status were predictors only for men, and depression and diabetes only for women. Conclusions: The identified differences by sex in cognitive trajectories and their associated factors suggest that men and women may require a different strategy when addressing cognitive aging.
000130195 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B15-17R$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/G03-128$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/01-0255$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/06-0617$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/98-0103$$9info:eu-repo/grantAgreement/ES/ISCIII-MINECO/PI16-00896$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI19-00948$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/03-0815$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/12-02254$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/16-00896$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/94-1562$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/97-1321E
000130195 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000130195 590__ $$a4.4$$b2023
000130195 592__ $$a1.913$$b2023
000130195 591__ $$aGERIATRICS & GERONTOLOGY$$b16 / 74 = 0.216$$c2023$$dQ1$$eT1
000130195 593__ $$aPsychiatry and Mental Health$$c2023$$dQ1
000130195 591__ $$aGERONTOLOGY$$b6 / 47 = 0.128$$c2023$$dQ1$$eT1
000130195 593__ $$aGeriatrics and Gerontology$$c2023$$dQ1
000130195 591__ $$aPSYCHIATRY$$b48 / 279 = 0.172$$c2023$$dQ1$$eT1
000130195 591__ $$aPSYCHIATRY$$b48 / 279 = 0.172$$c2023$$dQ1$$eT1
000130195 594__ $$a13.0$$b2023
000130195 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000130195 700__ $$0(orcid)0000-0002-9098-655X$$aLobo, Antonio$$uUniversidad de Zaragoza
000130195 700__ $$0(orcid)0000-0001-9822-6312$$aGracia-García, Patricia$$uUniversidad de Zaragoza
000130195 700__ $$0(orcid)0000-0002-3360-7015$$aLópez-Antón, Raúl$$uUniversidad de Zaragoza
000130195 700__ $$0(orcid)0000-0002-6427-6845$$aSaz, Pedro$$uUniversidad de Zaragoza
000130195 700__ $$0(orcid)0000-0003-2284-7862$$aDe la Cámara, Concepción$$uUniversidad de Zaragoza
000130195 7102_ $$14009$$2730$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Básica
000130195 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000130195 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000130195 773__ $$g31, 10 (2023), 796-807$$pAm. j. geriatr. psychiatry$$tAmerican journal of geriatric psychiatry$$x1064-7481
000130195 8564_ $$s401404$$uhttps://zaguan.unizar.es/record/130195/files/texto_completo.pdf$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2024-04-29
000130195 8564_ $$s1192903$$uhttps://zaguan.unizar.es/record/130195/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2024-04-29
000130195 909CO $$ooai:zaguan.unizar.es:130195$$particulos$$pdriver
000130195 951__ $$a2024-11-22-12:03:01
000130195 980__ $$aARTICLE