130295 20240130142253.0 doi 10.1016/j.jveb.2012.01.005 sideral 79024 ART-2012-79024 eng León, M. Assessment of serotonin in serum, plasma, and platelets of aggressive dogs 2012 Access copy available to the general public Unrestricted Canine aggression is the most common reason for the referral of dogs to behavior practices. In addition, dog bites represent an important problem for public health and animal welfare. The serotonergic system is believed to play an important role in modulating aggression. The aim of the present study was (1) to assess the suitability of different types of blood samples for measuring circulating serotonin in canine clinical studies, and (2) to investigate the relationship between the serotonergic system and canine aggression. The assessment of serotonin was simultaneously carried out in serum, plasma, and platelets of 28 aggressive and 10 nonaggressive dogs with an enzyme immunoassay technique. The mean serotonin concentration in aggressive dogs was significantly lower than in nonaggressive dogs in all the assayed samples. These findings suggest an inverse relationship between the activity of the serotonergic system and canine aggression. Considering the simplicity of the methodology, the authors propose sampling serum as the most suitable method for measuring circulating serotonin in dogs. info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 1.653 2012 VETERINARY SCIENCES 27 / 142 = 0.19 2012 Q1 T1 BEHAVIORAL SCIENCES 40 / 49 = 0.816 2012 Q4 T3 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Rosado, B. Universidad de Zaragoza (orcid)0000-0003-1728-900X García-Belenguer, S. Universidad de Zaragoza (orcid)0000-0001-5084-6555 Chacón, G. Villegas, A. Universidad de Zaragoza (orcid)0000-0001-8398-5463 Palacio, J. Universidad de Zaragoza (orcid)0000-0002-1581-3085 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 7, 6 (2012), 348-352 Journal of Veterinary Behavior-Clinical Applications and Research Journal of Veterinary Behavior 1558-7878 195122 http://zaguan.unizar.es/record/130295/files/texto_completo.pdf Postprint 781749 http://zaguan.unizar.es/record/130295/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:130295 articulos driver 2024-01-30-14:18:10 ARTICLE