130353 20240124152851.0 doi 10.1136/vr.140.18.477 sideral 101188 ART-1997-101188 eng Palacio J. (orcid)0000-0002-1581-3085 Enzymuria as an index of renal damage in canine leishmaniasis 1997 Urinary enzyme activities of alanine aminopeptidase, gammaglutamyl transpeptidase, alkaline phosphatase, N-acetyl-β-D-glucosaminidase and β-glucuronidase were determined in 15 dogs with leishmaniasis and in a group of eight normal dogs. Serum creatinine and blood urea nitrogen concentrations were also measured and renal histology was examined. All the affected dogs had renal lesions. However, no significant differences in blood urea nitrogen and creatinine concentrations were found between the control group and the affected group. The urinary enzyme activities of gamma-glutamyl transpeptidase (P<0.01), N-acetyl-β-D-glucosaminidase (P<0.01) and β-glucuronidase (P<0.05) were significantly higher in the affected dogs. Urinary enzymes therefore seem to be a more sensitive and reliable test for assessing early renal damage in canine leishmaniasis than serum creatinine or blood urea nitrogen concentrations. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 1.081 1997 VETERINARY SCIENCES 14 / 102 = 0.137 1997 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Liste F. Gascon M. Universidad de Zaragoza (orcid)0000-0002-5927-073X 1009 665 Universidad de Zaragoza Dpto. Patología Animal Area Patología Animal 140, 18 (1997), 477-480 Vet. rec. Veterinary Record 0042-4900 1047257 http://zaguan.unizar.es/record/130353/files/texto_completo.pdf Versión publicada 3438997 http://zaguan.unizar.es/record/130353/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130353 articulos driver 2024-01-24-15:05:00 ARTICLE