000130454 001__ 130454
000130454 005__ 20240125162930.0
000130454 0247_ $$2doi$$a10.3928/1081597X-20200713-02
000130454 0248_ $$2sideral$$a120310
000130454 037__ $$aART-2020-120310
000130454 041__ $$aeng
000130454 100__ $$0(orcid)0000-0002-3979-4528$$aRemón, L.$$uUniversidad de Zaragoza
000130454 245__ $$aBiomechanical Stability of Three Intraocular Lenses with Different Haptic Designs: In Silico and in Vivo Evaluation
000130454 260__ $$c2020
000130454 5203_ $$aPURPOSE:
To assess the biomechanical stability of three different marketed intraocular lenses (IOLs) with different haptic designs (four-loop IOL [Micro F FineVision model] and double C-loop IOL [POD F and POD FT models], all manufactured by PhysIOL), in silico (computer simulation) and in vivo (in the context of lens surgery).
METHODS:
An in silico simulation investigation was performed using finite element modeling (FEM) software to reproduce the compression test defined by the International Organization for Standardization and in vivo implantation in patients in the context of lens surgery was evaluated 1 day and 3 months postoperatively. IOL decentration and rotation were tested. In addition, the stress and strains were analyzed with the finite element method.
RESULTS:
In the in silico evaluation, the compression force for the POD F IOL was slightly lower than for the POD FT IOL and Micro F IOL for all compression diameters. The axial displacement was maximum for the POD FT IOL and the tilt, rotation, and lateral decentration were substantially lower than the acceptable tolerance limits established in ISO 11979-2. In the in vivo evaluation, a total of 45 eyes from 45 patients were selected, 15 eyes for each IOL model under assessment. Statistically significant differences were found between the Micro F and POD F IOLs for lateral decentration in x-direction (in absolute value) at 3 months postoperatively (P = .03).
CONCLUSIONS:
Although statistically significant differences have been found when comparing the displacement, tilt, and rotation between the different lenses, these differences cannot be considered clinically relevant, which would suggest that all three IOL models yield excellent stability in those terms. FEM appears to be a powerful tool for numerical studies of the biomechanical properties of IOLs.
000130454 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84047-R
000130454 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000130454 590__ $$a3.573$$b2020
000130454 591__ $$aSURGERY$$b53 / 210 = 0.252$$c2020$$dQ2$$eT1
000130454 591__ $$aOPHTHALMOLOGY$$b15 / 62 = 0.242$$c2020$$dQ1$$eT1
000130454 592__ $$a1.444$$b2020
000130454 593__ $$aSurgery$$c2020$$dQ1
000130454 593__ $$aOphthalmology$$c2020$$dQ1
000130454 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000130454 700__ $$0(orcid)0000-0001-8219-2365$$aCabeza-Gil, I.$$uUniversidad de Zaragoza
000130454 700__ $$0(orcid)0000-0001-9713-1813$$aCalvo, B.$$uUniversidad de Zaragoza
000130454 700__ $$aPoyales, F.
000130454 700__ $$aGarzón, N.
000130454 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000130454 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est.
000130454 773__ $$g36, 9 (2020), 617-624$$pJ. refract. surg.$$tJOURNAL OF REFRACTIVE SURGERY$$x1081-597X
000130454 8564_ $$s1782900$$uhttps://zaguan.unizar.es/record/130454/files/texto_completo.pdf$$yVersión publicada
000130454 8564_ $$s2685201$$uhttps://zaguan.unizar.es/record/130454/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000130454 909CO $$ooai:zaguan.unizar.es:130454$$particulos$$pdriver
000130454 951__ $$a2024-01-25-15:12:01
000130454 980__ $$aARTICLE