130454 20240125162930.0 doi 10.3928/1081597X-20200713-02 sideral 120310 ART-2020-120310 eng Remón, L. Universidad de Zaragoza (orcid)0000-0002-3979-4528 Biomechanical Stability of Three Intraocular Lenses with Different Haptic Designs: In Silico and in Vivo Evaluation 2020 PURPOSE: To assess the biomechanical stability of three different marketed intraocular lenses (IOLs) with different haptic designs (four-loop IOL [Micro F FineVision model] and double C-loop IOL [POD F and POD FT models], all manufactured by PhysIOL), in silico (computer simulation) and in vivo (in the context of lens surgery). METHODS: An in silico simulation investigation was performed using finite element modeling (FEM) software to reproduce the compression test defined by the International Organization for Standardization and in vivo implantation in patients in the context of lens surgery was evaluated 1 day and 3 months postoperatively. IOL decentration and rotation were tested. In addition, the stress and strains were analyzed with the finite element method. RESULTS: In the in silico evaluation, the compression force for the POD F IOL was slightly lower than for the POD FT IOL and Micro F IOL for all compression diameters. The axial displacement was maximum for the POD FT IOL and the tilt, rotation, and lateral decentration were substantially lower than the acceptable tolerance limits established in ISO 11979-2. In the in vivo evaluation, a total of 45 eyes from 45 patients were selected, 15 eyes for each IOL model under assessment. Statistically significant differences were found between the Micro F and POD F IOLs for lateral decentration in x-direction (in absolute value) at 3 months postoperatively (P = .03). CONCLUSIONS: Although statistically significant differences have been found when comparing the displacement, tilt, and rotation between the different lenses, these differences cannot be considered clinically relevant, which would suggest that all three IOL models yield excellent stability in those terms. FEM appears to be a powerful tool for numerical studies of the biomechanical properties of IOLs. info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84047-R info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 3.573 2020 SURGERY 53 / 210 = 0.252 2020 Q2 T1 OPHTHALMOLOGY 15 / 62 = 0.242 2020 Q1 T1 1.444 2020 Surgery 2020 Q1 Ophthalmology 2020 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Cabeza-Gil, I. Universidad de Zaragoza (orcid)0000-0001-8219-2365 Calvo, B. Universidad de Zaragoza (orcid)0000-0001-9713-1813 Poyales, F. Garzón, N. 2002 647 Universidad de Zaragoza Dpto. Física Aplicada Área Óptica 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 36, 9 (2020), 617-624 J. refract. surg. JOURNAL OF REFRACTIVE SURGERY 1081-597X 1782900 http://zaguan.unizar.es/record/130454/files/texto_completo.pdf Versión publicada 2685201 http://zaguan.unizar.es/record/130454/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130454 articulos driver 2024-01-25-15:12:01 ARTICLE