130473 20240125162930.0 doi 10.1016/j.mito.2011.08.002 sideral 75368 ART-2011-75368 eng Nogales-Gadea,G. Are mitochondrial haplogroups associated with elite athletic status? A study on a Spanish cohort 2011 There is increasing evidence regarding the association between mitochondrial DNA (mtDNA) and aerobic capacity; however, whether mtDNA haplogroups are associated with the status of being an elite endurance athlete is more controversial. We compared the frequency distribution of mtDNA haplogroups among the following groups of Spanish (Caucasian) men: 102 elite endurance athletes (professional road cyclists, endurance runners), 51 elite power athletes (jumpers, throwers and sprinters), and 478 non-athletic controls. We observed a significant difference between endurance athletes and controls (Fisher exact test = 17.89, P = 0.015; Bonferroni's significant threshold = 0.017), yet not between power athletes and controls (Fisher exact test = 47.99, P = 0.381) or between endurance and power athletes (Fisher exact test = 5.53, P = 0.597). We observed that the V haplogroup was overrepresented in endurance athletes (15.7%) compared with controls (7.5%) (odds ratio: 2.284; 95% confidence interval: 1.237, 4.322). In conclusion, our findings overall support the idea that mtDNA variations could be among the numerous contributors to the status of being an elite endurance athlete, whereas no association was found with elite power athletic status. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 3.615 2011 GENETICS & HEREDITY 45 / 156 = 0.288 2011 Q2 T1 CELL BIOLOGY 78 / 179 = 0.436 2011 Q2 T2 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pinós,T. Ruiz,J. R. Marzo,P. F. Fiuza-Luces,C. López-Gallardo,E. Universidad de Zaragoza (orcid)0000-0002-3217-1424 Ruiz-Pesini,E. Universidad de Zaragoza (orcid)0000-0002-0269-7337 Martín,M. A. Arenas,J. Morán,M. Andreu,A. L. Lucia,A. 1002 060 Universidad de Zaragoza Dpto. Bioq.Biolog.Mol. Celular Área Bioquímica y Biolog.Mole. 11, 6 (2011), 905-908 Mitochondrion MITOCHONDRION 1567-7249 161906 http://zaguan.unizar.es/record/130473/files/texto_completo.pdf Versión publicada 2786754 http://zaguan.unizar.es/record/130473/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130473 articulos driver 2024-01-25-15:13:31 ARTICLE