130499 20240125162931.0 doi 10.1016/j.drudis.2012.04.012 sideral 79061 ART-2012-79061 eng Pacheu-Grau,D. Universidad de Zaragoza (orcid)0000-0003-2645-3983 Read-through therapy for mitochondrial DNA nonsense mutations 2012 Disorders resulting from mitochondrial DNA (mtDNA) mutations, including nonsense mutations, do not yet have causal treatments. As we discuss here, read-through therapies appear to be a promising approach to the treatment of disorders arising from nuclear DNA (nDNA) nonsense mutations. The genetics of mitochondrial DNA suggest that this therapy will also be successful in the treatment of mitochondriopathies. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 6.551 2012 PHARMACOLOGY & PHARMACY 12 / 259 = 0.046 2012 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Gómez-Durán,A. Universidad de Zaragoza López-Gallardo,E. Universidad de Zaragoza (orcid)0000-0002-3217-1424 Montoya,J. Universidad de Zaragoza (orcid)0000-0003-1770-6299 Ruiz-Pesini,E. Universidad de Zaragoza (orcid)0000-0002-0269-7337 1008 566 Universidad de Zaragoza Dpto. Microb.Med.Pr.,Sal.Públ. Área Inmunología 1002 X Universidad de Zaragoza Dpto. Bioq.Biolog.Mol. Celular Proy. investigación DEA 1002 060 Universidad de Zaragoza Dpto. Bioq.Biolog.Mol. Celular Área Bioquímica y Biolog.Mole. 17, 19-20 (2012), 1063-1067 Drug discov. today DRUG DISCOVERY TODAY 1359-6446 141413 http://zaguan.unizar.es/record/130499/files/texto_completo.pdf Versión publicada 2230979 http://zaguan.unizar.es/record/130499/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130499 articulos driver 2024-01-25-15:15:41 ARTICLE