130508 20240125162931.0 doi 10.1309/0t2ukukv91w3qr6w sideral 129741 ART-2007-129741 eng Garcia, Mar (orcid)0000-0003-2078-8205 MALT Lymphoma Involving the Kidney 2007 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) can arise at any anatomic site, but involvement of the kidney is rare. We describe 10 cases of kidney MALT lymphoma, including 6 localized cases. No predisposing inflammatory conditions were identified, with the possible exception of coexistent renal Actinomyces infection in 1 case. We performed fluorescence in situ hybridization (FISH) using a malt1 break-apart probe in 7 cases. A malt1 gene rearrangement was identified in 1 case (14%). This case was further assessed by FISH using an IgH break-apart probe that showed IgH gene rearrangement. These results are suggestive of the t(14;18) involving malt1 and IgH. Immunostaining for NF- ¿B p65 showed nuclear positivity, consistent with NF- ¿B activation, in 3 of 5 cases assessed. Our results indicate that kidney MALT lymphomas share similarities with MALT lymphomas arising at other sites in that MALT lymphoma–associated translocations and NF- ¿B activation occur in a subset of cases. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 2.629 2007 PATHOLOGY 19 / 65 = 0.292 2007 Q2 T1 info:eu-repo/semantics/article Konoplev, Sergej Morosan, Cristian Abruzzo, Lynne V. Bueso-Ramos, Carlos E. Medeiros, L. Jeffrey 128, 3 (2007), 464-473 Am. j. clin. pathol. AMERICAN JOURNAL OF CLINICAL PATHOLOGY 0002-9173 8205699 http://zaguan.unizar.es/record/130508/files/texto_completo.pdf 2245405 http://zaguan.unizar.es/record/130508/files/texto_completo.jpg?subformat=icon icon oai:zaguan.unizar.es:130508 articulos driver 2024-01-25-15:16:26 ARTICLE