000130542 001__ 130542
000130542 005__ 20240130142255.0
000130542 0247_ $$2doi$$a10.5603/CJ.a2021.0085
000130542 0248_ $$2sideral$$a133296
000130542 037__ $$aART-2021-133296
000130542 041__ $$aeng
000130542 100__ $$aMelero Polo, Jorge$$uUniversidad de Zaragoza
000130542 245__ $$aEchocardiographic markers of cardiac amyloidosis in patients with heart failure and left ventricular hypertrophy
000130542 260__ $$c2021
000130542 5060_ $$aAccess copy available to the general public$$fUnrestricted
000130542 5203_ $$aBackground:
Cardiac amyloidosis (CA), following a non-invasive diagnosis, constitutes an increasingly prevalent heart failure (HF) etiology. This study aims to determine which echocardiography findings help to diagnose cardiac amyloidosis in patients with left ventricular hypertrophy (LVH) admitted for decompensated HF.
Methods:
The present study is a retrospective observational study on a cohort of 85 LVH patients admitted for HF decompensation, in which 99mTc-DPD scanning was performed to rule out transthyretin CA. The echocardiographic findings obtained were compared between CA and non-CA groups.
Results:
From a total number of 85 patients, 49 (57.6%) met the CA criteria and 36 (42.3%) were ruled out for the disease. Interventricular septum thickness (16 ± 3 mm vs. 14 ± 3 mm), left ventricular posterior wall thickness (14 ± 3 mm vs. 11 ± 2 mm), left ventricular mass (259 ± 76 g vs. 224 ± 53 g), left ventricular telediastolic diameter (48 ± 7 mm vs. 53 ± 6 mm), left ventricular telediastolic indexed volume (51 ± 18 cm3/m2 vs. 59 ± 16 cm3/m2), tricuspid annular plane systolic excursion (16 ± 5 mm vs. 20 ± 4 mm), right atrial area (27.4 ± 8.4 cm2 vs. 22.2 ± 5.7 cm2) and strain relative apical sparing (2.2 ± 0.9 vs. 1.03 ± 0.4; p = 0.04) were significantly associated with the diagnosis of CA.
Conclusions:
In patients with LVH admitted for HF decompensation, there are several echocardiographic features (LVH, reduced left ventricular cavity size, strain relative apical sparing, right atrial dilation, and altered right ventricular function) that are associated with the diagnosis of cardiac amyloidosis.
000130542 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000130542 590__ $$a3.487$$b2021
000130542 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b70 / 143 = 0.49$$c2021$$dQ2$$eT2
000130542 592__ $$a0.57$$b2021
000130542 593__ $$aMedicine (miscellaneous)$$c2021$$dQ2
000130542 593__ $$aCardiology and Cardiovascular Medicine$$c2021$$dQ2
000130542 594__ $$a3.8$$b2021
000130542 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000130542 700__ $$aRoteta Unceta-Barrenechea, Ana
000130542 700__ $$aRevilla Marti, Pablo$$uUniversidad de Zaragoza
000130542 700__ $$0(orcid)0000-0001-8655-9267$$aPerez-Palacios, Raquel$$uUniversidad de Zaragoza
000130542 700__ $$0(orcid)0000-0001-7136-2189$$aGracia Gutierrez, Anyuli$$uUniversidad de Zaragoza
000130542 700__ $$aBueno Juana, Esperanza
000130542 700__ $$0(orcid)0000-0003-3501-0121$$aAndres Gracia, Alejandro$$uUniversidad de Zaragoza
000130542 700__ $$0(orcid)0000-0003-0715-2843$$aAtienza Ayala, Saida$$uUniversidad de Zaragoza
000130542 700__ $$0(orcid)0000-0002-1774-6488$$aAibar Arregui, Miguel Angel
000130542 7102_ $$11011$$2770$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Radiol. y Medicina Física
000130542 7102_ $$11001$$2025$$aUniversidad de Zaragoza$$bDpto. Anatom.,Embri.Genét.Ani.$$cÁrea Anatom.Anatom.Patológ.Com
000130542 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000130542 773__ $$g30, 2 (2021), 266-275$$pCardiol. J.$$tCARDIOLOGY JOURNAL$$x1897-5593
000130542 8564_ $$s485516$$uhttps://zaguan.unizar.es/record/130542/files/texto_completo.pdf$$yVersión publicada
000130542 8564_ $$s3113234$$uhttps://zaguan.unizar.es/record/130542/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000130542 909CO $$ooai:zaguan.unizar.es:130542$$particulos$$pdriver
000130542 951__ $$a2024-01-30-14:19:40
000130542 980__ $$aARTICLE