130542 20240130142255.0 doi 10.5603/CJ.a2021.0085 sideral 133296 ART-2021-133296 eng Melero Polo, Jorge Universidad de Zaragoza Echocardiographic markers of cardiac amyloidosis in patients with heart failure and left ventricular hypertrophy 2021 Access copy available to the general public Unrestricted Background: Cardiac amyloidosis (CA), following a non-invasive diagnosis, constitutes an increasingly prevalent heart failure (HF) etiology. This study aims to determine which echocardiography findings help to diagnose cardiac amyloidosis in patients with left ventricular hypertrophy (LVH) admitted for decompensated HF. Methods: The present study is a retrospective observational study on a cohort of 85 LVH patients admitted for HF decompensation, in which 99mTc-DPD scanning was performed to rule out transthyretin CA. The echocardiographic findings obtained were compared between CA and non-CA groups. Results: From a total number of 85 patients, 49 (57.6%) met the CA criteria and 36 (42.3%) were ruled out for the disease. Interventricular septum thickness (16 ± 3 mm vs. 14 ± 3 mm), left ventricular posterior wall thickness (14 ± 3 mm vs. 11 ± 2 mm), left ventricular mass (259 ± 76 g vs. 224 ± 53 g), left ventricular telediastolic diameter (48 ± 7 mm vs. 53 ± 6 mm), left ventricular telediastolic indexed volume (51 ± 18 cm3/m2 vs. 59 ± 16 cm3/m2), tricuspid annular plane systolic excursion (16 ± 5 mm vs. 20 ± 4 mm), right atrial area (27.4 ± 8.4 cm2 vs. 22.2 ± 5.7 cm2) and strain relative apical sparing (2.2 ± 0.9 vs. 1.03 ± 0.4; p = 0.04) were significantly associated with the diagnosis of CA. Conclusions: In patients with LVH admitted for HF decompensation, there are several echocardiographic features (LVH, reduced left ventricular cavity size, strain relative apical sparing, right atrial dilation, and altered right ventricular function) that are associated with the diagnosis of cardiac amyloidosis. info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 3.487 2021 CARDIAC & CARDIOVASCULAR SYSTEMS 70 / 143 = 0.49 2021 Q2 T2 0.57 2021 Medicine (miscellaneous) 2021 Q2 Cardiology and Cardiovascular Medicine 2021 Q2 3.8 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Roteta Unceta-Barrenechea, Ana Revilla Marti, Pablo Universidad de Zaragoza Perez-Palacios, Raquel Universidad de Zaragoza (orcid)0000-0001-8655-9267 Gracia Gutierrez, Anyuli Universidad de Zaragoza (orcid)0000-0001-7136-2189 Bueno Juana, Esperanza Andres Gracia, Alejandro Universidad de Zaragoza (orcid)0000-0003-3501-0121 Atienza Ayala, Saida Universidad de Zaragoza (orcid)0000-0003-0715-2843 Aibar Arregui, Miguel Angel (orcid)0000-0002-1774-6488 1011 770 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Radiol. y Medicina Física 1001 025 Universidad de Zaragoza Dpto. Anatom.,Embri.Genét.Ani. Área Anatom.Anatom.Patológ.Com 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 30, 2 (2021), 266-275 Cardiol. J. CARDIOLOGY JOURNAL 1897-5593 485516 http://zaguan.unizar.es/record/130542/files/texto_completo.pdf Versión publicada 3113234 http://zaguan.unizar.es/record/130542/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130542 articulos driver 2024-01-30-14:19:40 ARTICLE