130753 20240131210810.0 doi 10.1016/j.ibiod.2018.04.004 sideral 106573 ART-2019-106573 eng Franco Castillo, Isabel (orcid)0000-0002-8263-0473 Protection of 18th century paper using antimicrobial nano-magnesium oxide 2019 Magnesium oxide nanoparticles (MgO NPs) have attracted considerable interest as antimicrobial agents in a wide variety of applications. We report a simple synthetic route towards MgO NPs (average diameter 10 nm) possessing potent antibacterial activity against both Gram-negative and Gram-positive bacteria. Detailed electron microscopy studies show how these particles induce oxidative stress, cell membrane leakage and cell death in bacteria at low NP concentrations, but remain non-toxic to eukaryotic cells. Applying a homogeneous dispersion of these nanoparticles on 18th century paper proved to be a highly effective means of preventing bacterial colonisation without altering the appearance of the paper samples, thus opening the doors to the use of these colourless, low-cost, and scalable nanoparticles for preventing biodeterioration in a range of paper-based objects and surfaces. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 4.074 2019 BIOTECHNOLOGY & APPLIED MICROBIOLOGY 36 / 156 = 0.231 2019 Q1 T1 ENVIRONMENTAL SCIENCES 66 / 264 = 0.25 2019 Q1 T1 1.172 2019 Biomaterials 2019 Q1 Waste Management and Disposal 2019 Q1 Microbiology 2019 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion De Matteis, Laura (orcid)0000-0001-6995-4302 Marquina, Clara Universidad de Zaragoza (orcid)0000-0003-0602-492X García Guillén, Esther Martínez de la Fuente, Jesús (orcid)0000-0003-1081-8482 Mitchell, Scott G. Universidad de Zaragoza (orcid)0000-0003-4848-414X 2013 765 Universidad de Zaragoza Dpto. Química Orgánica Área Química Orgánica 2003 395 Universidad de Zaragoza Dpto. Física Materia Condensa. Área Física Materia Condensada 141 (2019), 79-86 Int. biodeterior. biodegrad. INTERNATIONAL BIODETERIORATION & BIODEGRADATION 0964-8305 1533694 http://zaguan.unizar.es/record/130753/files/texto_completo.pdf Postprint 2381417 http://zaguan.unizar.es/record/130753/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:130753 articulos driver 2024-01-31-19:18:06 ARTICLE