130799 20240131210811.0 doi 10.1016/j.talanta.2021.122603 sideral 126047 ART-2021-126047 eng Ubeda, Sara Universidad de Zaragoza (orcid)0000-0002-9804-8699 Fabric phase sorptive extraction for specific migration analysis of oligomers from biopolymers 2021 Oligomers are potential migrants from polymers or biopolymers intended to food packaging and they have to be under control. In order to comply with European regulation 10/2011, their concentration in migration must be below 0.01 mu g g(-1). In this work, fabric phase sorptive extraction (FPSE) was explored as an effective method for extraction and pre-concentration of oligomers migrated from a blend PLA-polyester material. Both food simulant B (3% acetic acid) and juice, as real food, were used for migration experiments. The parameters of FPSE were optimized and the analysis was done by UHPLC-QTOF and UHPLC-QqQ. A total of 21 oligomers were identified, 9 of them coming from PLA and 12 oligomers from the polyester part. These oligomers were formed by adipic acid (AA), phthalic acid (PA) and/or butanediol (BD), ten were cyclic and 11 were linear molecules. Using the optimized FPSE procedure in 3% acetic acid as food simulant, it was possible to identify 3 new compounds that were not detected by direct injection of the simulant into UHPLC-QTOF. In addition, 2 extra compounds, cyclic PA-BD4-AA(3) and cyclic PA(2)-BD3-AA, were only identified in juice samples after FPSE extraction. Besides, in order to quantify the compounds identified, an isolation procedure for PLA oligomers was carried out. Two oligomers were isolated: cyclic (LA)(6) and linear HO-(LA)(4)-H, both with a purity higher than 90% (LA: lactic acid). The highest concentration value was found for the cyclic oligomer [AA-BD](2), that showed 22.63 mu g g(-1) in 3% acetic acid and 19.64 mu g g(-1) in juice. The concentration of the total amount of remaining oligomers was below 7.56 mu g g(-1) in 3% acetic acid as well as in juice. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/DGA-FSE/T53-20R info:eu-repo/grantAgreement/ES/MINECO/BES-2016-077159 info:eu-repo/grantAgreement/ES/MINECO/RTI2018-097805-B-I00 info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 6.556 2021 CHEMISTRY, ANALYTICAL 11 / 87 = 0.126 2021 Q1 T1 0.983 2021 Spectroscopy 2021 Q1 Analytical Chemistry 2021 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Aznar, Margarita Universidad de Zaragoza (orcid)0000-0002-0759-9170 Nerin, Cristina Universidad de Zaragoza (orcid)0000-0003-2685-5739 Kabir, Abizar 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 233 (2021), 122603 [8 pp.] Talanta Talanta 0039-9140 1779929 http://zaguan.unizar.es/record/130799/files/texto_completo.pdf Versión publicada 2469384 http://zaguan.unizar.es/record/130799/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130799 articulos driver 2024-01-31-19:22:00 ARTICLE