000130864 001__ 130864
000130864 005__ 20240201151019.0
000130864 0247_ $$2doi$$a10.1109/TBME.2017.2711645
000130864 0248_ $$2sideral$$a102363
000130864 037__ $$aART-2017-102363
000130864 041__ $$aeng
000130864 100__ $$0(orcid)0000-0003-0226-4950$$aMartín-Yebra, Alba$$uUniversidad de Zaragoza
000130864 245__ $$aPost-ventricular premature contraction phase correction improves the predictive value of average T-wave alternans in ambulatory ECG recordings.
000130864 260__ $$c2017
000130864 5060_ $$aAccess copy available to the general public$$fUnrestricted
000130864 5203_ $$aObjective: We proposed and evaluated a method for correcting possible phase-shifts provoked by the presence of ventricular premature contractions (VPCs) for a better assessment of T wave alternans (TWA). Methods: First, we synthesized ECG signals with artificial TWA in the presence of different noise sources. Then, we assessed the prognostic value for sudden cardiac death (SCD) of the long-term average of TWA amplitude, (the index of average alternans, IAA) in ambulatory ECG signals from congestive heart failure (CHF) and evaluated whether it is sensitive to the presence of VPCs. Results: The inclusion of the phase correction after VPC in the processing always improved estimation accuracy of the IAA under different noisy conditions and regardless of the number of the VPCs included in the sequence. It presented also a positive impact in the prognostic value of IAA with increased hazard ratios (from 17% to 29%, depending of the scenario) in comparison to the non-inclusion of this step. Conclusion: the proposed methodology for IAA estimation, which corrects for the possible phase reversal on TWA after the presence of VPCs, represents a robust TWA estimation approach with a significant impact in the prognostic value of IAA for SCD stratification in CHF patients. Significance: an accurate TWA estimation has a potential direct clinical impact in non-invasive SCD stratification, allowing better identification of patients at higher risk and helping clinicians in adopting the most appropriate therapeutic strategy.
000130864 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000130864 590__ $$a4.288$$b2017
000130864 591__ $$aENGINEERING, BIOMEDICAL$$b9 / 77 = 0.117$$c2017$$dQ1$$eT1
000130864 592__ $$a1.267$$b2017
000130864 593__ $$aBiomedical Engineering$$c2017$$dQ1
000130864 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000130864 700__ $$0(orcid)0000-0001-5343-5671$$aMonasterio, Violeta
000130864 700__ $$aIwona Cygankiewicz
000130864 700__ $$aBayés-de-Luna, Antonio
000130864 700__ $$aCaiani, Enrico
000130864 700__ $$0(orcid)0000-0003-3434-9254$$aLaguna, Pablo$$uUniversidad de Zaragoza
000130864 700__ $$0(orcid)0000-0002-7503-3339$$aMartínez, Juan Pablo$$uUniversidad de Zaragoza
000130864 7102_ $$15008$$2X$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cProy. investigación JBA
000130864 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000130864 773__ $$g65, 3 (2017), 635-644$$pIEEE trans. biomed. eng.$$tIEEE Transactions on Biomedical Engineering$$x0018-9294
000130864 8564_ $$s855725$$uhttps://zaguan.unizar.es/record/130864/files/texto_completo.pdf$$yPostprint
000130864 8564_ $$s3503780$$uhttps://zaguan.unizar.es/record/130864/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000130864 909CO $$ooai:zaguan.unizar.es:130864$$particulos$$pdriver
000130864 951__ $$a2024-02-01-14:35:35
000130864 980__ $$aARTICLE