000130886 001__ 130886
000130886 005__ 20240201151019.0
000130886 0247_ $$2doi$$a10.1016/j.talanta.2020.121408
000130886 0248_ $$2sideral$$a119086
000130886 037__ $$aART-2020-119086
000130886 041__ $$aeng
000130886 100__ $$aMandrile, L.
000130886 245__ $$aMigration study of organotin compounds from food packaging by surface-enhanced Raman scattering
000130886 260__ $$c2020
000130886 5060_ $$aAccess copy available to the general public$$fUnrestricted
000130886 5203_ $$aThe potential of surface-enhanced Raman scattering (SERS) has been investigated for the rapid analysis of two representative organotin compounds (OTCs): dibutyltin maleate (DTM) and tributyltin chloride (TBT), after migration tests from polyvinyl chloride (PVC), as a model food packaging material in aqueous food simulant (acetic acid 3% w/v). OTCs, often used as heat stabilizers additives for PVC, are classified as endocrine disrupting chemicals (EDCs) and their migration potential has to be controlled in compliance with the normative prescriptions for food contact materials. In this study, colloidal silver nanoparticles (AgNPs) were applied as liquid SERS substrate for direct-in-liquid analysis of food simulant after standardized migration tests of PVC samples spiked with OTCs. Promising results were obtained, reaching detection limits below the permitted limits for the considered OTCs (i.e. 0.15 mg/l): DTM and TBT were detected down to 0.01 mg/l and 0.08 mg/l, respectively. Calibration curves were calculated for standard solutions of DTM and TBT in the dynamic range between 0 and 1 mg/l (reduced ¿2 = 0.8), and 0.5–5 mg/l (reduced ¿2 = 0.2), respectively. Migrated TBT and DTM were detected in the food simulant, specifically identified and quantified by SERS, with a measurement uncertainty around 10% in all cases. In particular, it was found that TBT can migrate in higher amount compared to DTM when the PVC film is in contact with a slightly acidic matrix. These results were further confirmed by inductively coupled plasma-mass spectrometry and UV–Vis spectroscopy. In the present study, direct-in-liquid SERS approach showed to be very promising because it provides a fast response and it allows to overcome most of the common drawbacks of solid SERS substrates due to inhomogeneity problems and low repeatability.
000130886 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000130886 590__ $$a6.057$$b2020
000130886 591__ $$aCHEMISTRY, ANALYTICAL$$b12 / 83 = 0.145$$c2020$$dQ1$$eT1
000130886 592__ $$a1.181$$b2020
000130886 593__ $$aAnalytical Chemistry$$c2020$$dQ1
000130886 593__ $$aSpectroscopy$$c2020$$dQ1
000130886 593__ $$aBiochemistry$$c2020$$dQ1
000130886 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000130886 700__ $$aVona, M.
000130886 700__ $$aGiovannozzi, A.M.
000130886 700__ $$0(orcid)0000-0002-6607-1309$$aSalafranca, J.$$uUniversidad de Zaragoza
000130886 700__ $$aMartra, G.
000130886 700__ $$aRossi, A.M.
000130886 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica
000130886 773__ $$g220 (2020), 121408 1-9$$pTalanta$$tTalanta$$x0039-9140
000130886 8564_ $$s2059177$$uhttps://zaguan.unizar.es/record/130886/files/texto_completo.pdf$$yPostprint
000130886 8564_ $$s2587070$$uhttps://zaguan.unizar.es/record/130886/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000130886 909CO $$ooai:zaguan.unizar.es:130886$$particulos$$pdriver
000130886 951__ $$a2024-02-01-14:38:11
000130886 980__ $$aARTICLE