000130982 001__ 130982 000130982 005__ 20240202151703.0 000130982 0247_ $$2doi$$a10.1109/TII.2020.2972111 000130982 0248_ $$2sideral$$a120476 000130982 037__ $$aART-2020-120476 000130982 041__ $$aeng 000130982 100__ $$aGarcia-Camprubi, M. 000130982 245__ $$aVirtual sensor development for continuous microfluidic processes 000130982 260__ $$c2020 000130982 5203_ $$aIn continuous microfluidic processes, such as factory-on-chips, most valuable variables to be sensed for implementing an optimal control are usually not accessible. This is, for instance, the case of the shape and position tracking of the flow interfaces in a flow-focusing microdevice. In this context, virtual sensors are promising tools to improve the current control systems aiming at a zero-defect strategy. This article presents a methodology for building an accurate virtual sensor, based on computer-aided engineering simulations, both analytical and numerical, and model order reduction techniques. The methodology is applied to a given flow-focusing microchip. The outcome is a real-time model (virtual sensor) able to predict the shape and location of the multiphase fluid interfaces from the volumetric flow rate measured in the system. Results are successfully validated against the experimental data. The main challenge of this approach is to minimize uncertainties associated with the microfluidics setup. 000130982 536__ $$9info:eu-repo/grantAgreement/EC/H2020/680481/EU/Third tranche of Success Stories/Fortissimo 2$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 680481-Fortissimo 2 000130982 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000130982 590__ $$a10.215$$b2020 000130982 591__ $$aAUTOMATION & CONTROL SYSTEMS$$b4 / 63 = 0.063$$c2020$$dQ1$$eT1 000130982 591__ $$aENGINEERING, INDUSTRIAL$$b1 / 49 = 0.02$$c2020$$dQ1$$eT1 000130982 591__ $$aCOMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS$$b3 / 111 = 0.027$$c2020$$dQ1$$eT1 000130982 592__ $$a2.496$$b2020 000130982 593__ $$aComputer Science Applications$$c2020$$dQ1 000130982 593__ $$aInformation Systems$$c2020$$dQ1 000130982 593__ $$aElectrical and Electronic Engineering$$c2020$$dQ1 000130982 593__ $$aControl and Systems Engineering$$c2020$$dQ1 000130982 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000130982 700__ $$aBengoechea-Cuadrado, C. 000130982 700__ $$0(orcid)0000-0001-6906-9143$$aIzquierdo, S. 000130982 773__ $$g16, 12 (2020), 7774-7781$$pIEEE Trans. Ind. Inform.$$tIEEE Transactions on Industrial Informatics$$x1551-3203 000130982 8564_ $$s2550281$$uhttps://zaguan.unizar.es/record/130982/files/texto_completo.pdf$$yVersión publicada 000130982 8564_ $$s4243210$$uhttps://zaguan.unizar.es/record/130982/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000130982 909CO $$ooai:zaguan.unizar.es:130982$$particulos$$pdriver 000130982 951__ $$a2024-02-02-14:51:06 000130982 980__ $$aARTICLE