000131042 001__ 131042 000131042 005__ 20240705134149.0 000131042 0247_ $$2doi$$a10.1016/j.bpsc.2023.05.008 000131042 0248_ $$2sideral$$a136677 000131042 037__ $$aART-2024-136677 000131042 041__ $$aeng 000131042 100__ $$aPozzi, Elena 000131042 245__ $$aInvestigating associations between maternal behavior and the development of functional connectivity during the transition from late childhood to early adolescence 000131042 260__ $$c2024 000131042 5203_ $$aBackground: Parenting behavior is thought to affect child brain development, with implications for mental health. However, longitudinal studies that use whole-brain approaches are lacking. In this study, we investigated associations between parenting behavior, age-related changes in whole-brain functional connectivity, and psychopathology symptoms in children and adolescents. Methods: Two hundred forty (126 female) children underwent resting-state functional magnetic resonance imaging at up to two time points, providing a total of 398 scans covering the age range 8 to 13 years. Parenting behavior was self-reported at baseline. Parenting factors (positive parenting, inattentive parenting, and harsh and inconsistent discipline) were identified based on a factor analysis of self-report parenting questionnaires. Longitudinal measures of child internalizing and externalizing symptoms were collected. Network-based R-statistics was used to identify associations between parenting and age-related changes in functional connectivity. Results: Higher maternal inattentive behavior was associated with lower decreases in connectivity over time, particularly between regions of the ventral attention and default mode networks and frontoparietal and default mode networks. However, this association was not significant after strict correction for multiple comparisons. Conclusions: While results should be considered preliminary, they suggest that inattentive parenting may be associated with a reduction in the normative pattern of increased network specialization that occurs with age. This may reflect a delayed development of functional connectivity. 000131042 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000131042 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000131042 700__ $$aRakesh, Divyangana 000131042 700__ $$0(orcid)0000-0003-2461-8588$$aGracia-Tabuenca, Zeus$$uUniversidad de Zaragoza 000131042 700__ $$aBray, Katherine O. 000131042 700__ $$aRichmond, Sally 000131042 700__ $$aSeal, Marc L. 000131042 700__ $$aSchwartz, Orli 000131042 700__ $$aVijayakumar, Nandita 000131042 700__ $$aYap, Marie B.H. 000131042 700__ $$aWhittle, Sarah 000131042 7102_ $$12007$$2265$$aUniversidad de Zaragoza$$bDpto. Métodos Estadísticos$$cÁrea Estadís. Investig. Opera. 000131042 773__ $$g9, 4 (2024), 398-406$$tBiological Psychiatry: Cognitive Neuroscience and Neuroimaging$$x2451-9022 000131042 8564_ $$s933798$$uhttps://zaguan.unizar.es/record/131042/files/texto_completo.pdf$$yPostprint 000131042 8564_ $$s3087827$$uhttps://zaguan.unizar.es/record/131042/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000131042 909CO $$ooai:zaguan.unizar.es:131042$$particulos$$pdriver 000131042 951__ $$a2024-07-05-12:48:09 000131042 980__ $$aARTICLE