000131102 001__ 131102 000131102 005__ 20240206150120.0 000131102 0247_ $$2doi$$a10.1103/PhysRevX.4.041005 000131102 0248_ $$2sideral$$a136738 000131102 037__ $$aART-2014-136738 000131102 041__ $$aeng 000131102 100__ $$0(orcid)0000-0002-2980-9685$$aSanz, Joaquín$$uUniversidad de Zaragoza 000131102 245__ $$aDynamics of interacting diseases 000131102 260__ $$c2014 000131102 5060_ $$aAccess copy available to the general public$$fUnrestricted 000131102 5203_ $$aCurrent modeling of infectious diseases allows for the study of complex and realistic scenarios that go from the population to the individual level of description. However, most epidemic models assume that the spreading process takes place on a single level (be it a single population, a metapopulation system, or a network of contacts). In particular, interdependent contagion phenomena can be addressed only if we go beyond the scheme-one pathogen-one network. In this paper, we propose a framework that allows us to describe the spreading dynamics of two concurrent diseases. Specifically, we characterize analytically the epidemic thresholds of the two diseases for different scenarios and compute the temporal evolution characterizing the unfolding dynamics. Results show that there are regions of the parameter space in which the onset of a disease’s outbreak is conditioned to the prevalence levels of the other disease. Moreover, we show, for the susceptible-infected-susceptible scheme, that under certain circumstances, finite and not vanishing epidemic thresholds are found even at the limit for scale-free networks. For the susceptible-infected-removed scenario, the phenomenology is richer and additional interdependencies show up. We also find that the secondary thresholds for the susceptible-infected-susceptible and susceptible-infected-removed models are different, which results directly from the interaction between both diseases. Our work thus solves an important problem and paves the way toward a more comprehensive description of the dynamics of interacting diseases. 000131102 536__ $$9info:eu-repo/grantAgreement/EC/FP7/317532/EU/Foundational Research on MULTIlevel comPLEX networks and systems/MULTIPLEX$$9info:eu-repo/grantAgreement/EC/FP7/317614/EU/Mathematical framework for multiplex networks/PLEXMATH$$9info:eu-repo/grantAgreement/ES/MINECO/FIS2011-25167 000131102 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000131102 590__ $$a9.043$$b2014 000131102 591__ $$aPHYSICS, MULTIDISCIPLINARY$$b5 / 78 = 0.064$$c2014$$dQ1$$eT1 000131102 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000131102 700__ $$aXia, Cheng-Yi 000131102 700__ $$0(orcid)0000-0001-6202-3302$$aMeloni, Sandro$$uUniversidad de Zaragoza 000131102 700__ $$0(orcid)0000-0002-0895-1893$$aMoreno, Yamir$$uUniversidad de Zaragoza 000131102 7102_ $$12004$$2405$$aUniversidad de Zaragoza$$bDpto. Física Teórica$$cÁrea Física Teórica 000131102 773__ $$g4, 4 (2014)$$pPhysical review. X$$tPhysical review. X$$x2160-3308 000131102 8564_ $$s4763169$$uhttps://zaguan.unizar.es/record/131102/files/texto_completo.pdf$$yVersión publicada 000131102 8564_ $$s2835964$$uhttps://zaguan.unizar.es/record/131102/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000131102 909CO $$ooai:zaguan.unizar.es:131102$$particulos$$pdriver 000131102 951__ $$a2024-02-06-14:56:37 000131102 980__ $$aARTICLE