000131134 001__ 131134
000131134 005__ 20240205173707.0
000131134 0247_ $$2doi$$a10.1378/chest.11-2413
000131134 0248_ $$2sideral$$a136398
000131134 037__ $$aART-2012-136398
000131134 041__ $$aeng
000131134 100__ $$aAlmagro, Pedro
000131134 245__ $$aComorbidities and short-term prognosis in patients hospitalized for acute exacerbation of COPD: The EPOC en Servicios de Medicina Interna (ESMI) Study
000131134 260__ $$c2012
000131134 5060_ $$aAccess copy available to the general public$$fUnrestricted
000131134 5203_ $$aBackground: Comorbidities are frequent in patients hospitalized for COPD exacerbation, but little is known about their relation with short-term mortality and hospital readmissions. Our hypothesis is that the frequency and type of comorbidities impair the prognosis within 12 weeks after discharge.
Methods: A longitudinal, observational, multicenter study of patients hospitalized for a COPD exacerbation with spirometric confirmation was performed. Comorbidity information was collected using the Charlson index and a questionnaire that included other common conditions not included in this index. Dyspnea, functional status, and previous hospitalization for COPD or other reasons among other variables were investigated. Information on mortality and readmissions for COPD or other causes was collected up to 3 months after discharge.
Results: We studied 606 patients, 594 men (89.9%), with a mean (SD) age of 72.6 (9.9) years and a postbronchodilator FEV1 of 43.2% (21.2). The mean Charlson index score was 3.1 (2.0). On admission, 63.4% of patients had arterial hypertension, 35.8% diabetes mellitus, 32.8% chronic heart failure, 20.8% ischemic heart disease, 19.3% anemia, and 34% dyslipemia. Twenty-seven patients (4.5%) died within 3 months. The Charlson index was an independent predictor of mortality (P < .003; OR,1.23; 95% CI, 1.07-1.40), even after adjustment for age, FEV1, and functional status measured with the Katz index. Comorbidity was also related with the need for hospitalization from the ED, length of stay, and hospital readmissions for COPD or other causes.
Conclusions: Comorbidities are common in patients hospitalized for a COPD exacerbation, and they are related to short-term prognosis.
000131134 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000131134 590__ $$a5.854$$b2012
000131134 591__ $$aCRITICAL CARE MEDICINE$$b3 / 26 = 0.115$$c2012$$dQ1$$eT1
000131134 591__ $$aRESPIRATORY SYSTEM$$b4 / 50 = 0.08$$c2012$$dQ1$$eT1
000131134 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000131134 700__ $$aCabrera, Francisco Javier
000131134 700__ $$0(orcid)0000-0002-3132-2171$$aDiez Manglano, Jesús$$uUniversidad de Zaragoza
000131134 700__ $$aBoixeda, Ramón
000131134 700__ $$aAlonso Martín, Belén M.
000131134 700__ $$aMurio, Cristina
000131134 700__ $$aSoriano, Joan S.
000131134 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000131134 773__ $$g142, 5 (2012), 1126-1132$$pChest$$tChest$$x0012-3692
000131134 8564_ $$s286864$$uhttps://zaguan.unizar.es/record/131134/files/texto_completo.pdf$$yPostprint
000131134 8564_ $$s1356582$$uhttps://zaguan.unizar.es/record/131134/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000131134 909CO $$ooai:zaguan.unizar.es:131134$$particulos$$pdriver
000131134 951__ $$a2024-02-05-15:07:01
000131134 980__ $$aARTICLE