131308 20240208113739.0 doi 10.1109/BIBM.2018.8621358 sideral 127500 ART-2018-127500 eng Marin, Belen Evolution of GWAS results through ADNI cohorts 2018 Access copy available to the general public Unrestricted Genome Wide Association Studies (GWAS) of Alzheimer's disease with quantitative phenotype is an active field of research that has pointed out a number of SNPs potentially related to the disease. Some initiatives such as Alzheimer's Disease Neuroimaging Initiative (ADNI) have been established in order to proof whether anatomical or biological markers (from magnetic resonance imaging (MRI) or positron emission tomography (PET)), genetic information, and clinical and neuropsychological assessments can be combined to measure the progression of mild cognitive impairment (MCI) and early Alzheimer's disease (AD). In the last decade, ADNI database has been progressively augmented, including a considerable number of patients yielding to the subsequent projects and cohorts ADNI1, ADNIGO, and ADNI2. Although some GWAS have been carried out with subpopulations of ADNI1, to the best of our knowledge, these works have not been replicated with the whole ADNI1 or the subsequent cohorts. In this work, we intend to study which SNPs are consistently preserved through ADNI cohorts in GWAS. info:eu-repo/grantAgreement/ES/MINECO/BES-2017-079979 info:eu-repo/grantAgreement/ES/MINECO/TIN2016-80347-R info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ info:eu-repo/semantics/conferenceObject info:eu-repo/semantics/acceptedVersion Alquezar-Baeta, Carlos Universidad de Zaragoza (orcid)0000-0003-0389-2422 Hernandez, Monica Universidad de Zaragoza (orcid)0000-0003-1270-5852 Mayordomo Cámara, Elvira Universidad de Zaragoza (orcid)0000-0002-9109-5337 5007 570 Universidad de Zaragoza Dpto. Informát.Ingenie.Sistms. Área Lenguajes y Sistemas Inf. (2018), 2782-2784 Proceedings (IEEE Int. Conf. Bioinformatics Biomed.) Proceedings (IEEE International Conference on Bioinformatics and Biomedicine) 2156-1125 211726 http://zaguan.unizar.es/record/131308/files/texto_completo.pdf Postprint 2511972 http://zaguan.unizar.es/record/131308/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:131308 articulos driver 2024-02-08-10:52:58 ARTICLE