000131311 001__ 131311
000131311 005__ 20240207154753.0
000131311 0247_ $$2doi$$a10.1007/s00520-021-06343-1
000131311 0248_ $$2sideral$$a127475
000131311 037__ $$aART-2021-127475
000131311 041__ $$aeng
000131311 100__ $$aLópez-Rodríguez-Arias F.
000131311 245__ $$aEffect of home-based prehabilitation in an enhanced recovery after surgery program for patients undergoing colorectal cancer surgery during the COVID-19 pandemic
000131311 260__ $$c2021
000131311 5203_ $$aBackground: Surgery remains the first curative treatment for colorectal cancer. Prehabilitation seems to attenuate the loss of lean mass in the early postoperative period. However, its long-term role has not been studied. Lockdown due to the COVID-19 pandemic has forced to carry out the prehabilitation program at home. This study aimed to assess the effect of home prehabilitation on body composition, complications, and hospital stay in patients undergoing oncological colorectal surgery.
Methods: A prospective and randomized clinical study was conducted in 20 patients operated of colorectal cancer during COVID-19 lockdown (13 March to 21 June 2020) in a single university clinical hospital. Patients were randomized into two study groups (10 per group): prehabilitation vs standard care. Changes in lean mass and fat mass at 45 and 90 days after surgery were measured using multifrequency bioelectrical impedance analysis.
Results: Prehabilitation managed to reduce hospital stay (4.8 vs 7.2 days, p = 0.052) and postoperative complications (20% vs 50%, p = 0.16). Forty-five days after surgery, the loss of lean mass decreased (1.7% vs 7.1%, p = 0.17). These differences in lean mass were attenuated at 90 days; however, the standard care group increased considerably their fat mass compared to the prehabilitation group (+ 8.72% vs - 8.16%).
Conclusions: Home prehabilitation has proven its effectiveness, achieving an attenuation of lean mass loss in the early postoperative period and a lower gain in fat mass in the late postoperative period. In addition, it has managed to reduce hospital stays and postoperative complications. Registration number: This article is part of an ongoing, randomized, and controlled clinical trial approved by the ethics committee of our hospital and registered in ClinicalTrials.gov in August 2018 with registration number NCT03618329. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
000131311 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000131311 590__ $$a3.359$$b2021
000131311 591__ $$aREHABILITATION$$b17 / 68 = 0.25$$c2021$$dQ1$$eT1
000131311 591__ $$aHEALTH CARE SCIENCES & SERVICES$$b45 / 109 = 0.413$$c2021$$dQ2$$eT2
000131311 591__ $$aONCOLOGY$$b164 / 245 = 0.669$$c2021$$dQ3$$eT3
000131311 592__ $$a0.949$$b2021
000131311 593__ $$aOncology$$c2021$$dQ2
000131311 594__ $$a4.9$$b2021
000131311 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000131311 700__ $$aSánchez-Guillén L.
000131311 700__ $$aAranaz-Ostáriz V.
000131311 700__ $$aTriguero-Cánovas D.
000131311 700__ $$aLario-Pérez S.
000131311 700__ $$aBarber-Valles X.
000131311 700__ $$aLacueva F.J.
000131311 700__ $$0(orcid)0000-0001-7964-1166$$aRamirez J.M.$$uUniversidad de Zaragoza
000131311 700__ $$aArroyo A.
000131311 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000131311 773__ $$g29, 12 (2021), 7785-7791$$pSupport. care cancer$$tSUPPORTIVE CARE IN CANCER$$x0941-4355
000131311 8564_ $$s536727$$uhttps://zaguan.unizar.es/record/131311/files/texto_completo.pdf$$yPostprint
000131311 8564_ $$s2059764$$uhttps://zaguan.unizar.es/record/131311/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000131311 909CO $$ooai:zaguan.unizar.es:131311$$particulos$$pdriver
000131311 951__ $$a2024-02-07-14:39:34
000131311 980__ $$aARTICLE