131363 20240208115248.0 doi 10.1016/j.maturitas.2018.10.014 sideral 108993 ART-2019-108993 eng Santabárbara, J. Universidad de Zaragoza (orcid)0000-0002-7297-6104 Anxiety and risk of dementia: Systematic review and meta-analysis of prospective cohort studies 2019 Objectives: Anxiety is postulated to be modifiable risk factor for dementia. Our primary aim was to conduct a meta-analysis of community-based cohort studies that investigated the association between anxiety and dementia. Design: We identified relevant, high-quality papers published up to January 2018 by searching PubMed and Web of Science. Prospective cohort studies reporting relative risks (RRs) for the association between anxiety and dementia, adjusted at least for age, were considered eligible. Study-specific RRs were combined using a random-effects model. Results: Six prospective cohorts (reported in 5 studies), with a total of 10, 394 participants, were included in the meta-analysis. The pooled RR of 1.29 (95% CI: 1.01–1.66) indicated a significant association between anxiety and dementia. Conclusion: Anxiety significantly increases the risk of dementia. However, further research is needed to determine the extent to which anxiety is a cause of dementia rather than a prodrome or marker. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 3.63 2019 OBSTETRICS & GYNECOLOGY 12 / 82 = 0.146 2019 Q1 T1 GERIATRICS & GERONTOLOGY 14 / 51 = 0.275 2019 Q2 T1 1.189 2019 Obstetrics and Gynecology 2019 Q1 Biochemistry, Genetics and Molecular Biology (miscellaneous) 2019 Q1 info:eu-repo/semantics/review info:eu-repo/semantics/acceptedVersion Lipnicki, D.M. Villagrasa, B. Lobo, E. Universidad de Zaragoza (orcid)0000-0002-1252-2397 Lopez-Anton, R. Universidad de Zaragoza (orcid)0000-0002-3360-7015 4009 730 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Básica 1008 615 Universidad de Zaragoza Dpto. Microb.Med.Pr.,Sal.Públ. Área Medic.Prevent.Salud Públ. 119 (2019), 14-20 Maturitas Maturitas 0378-5122 584679 http://zaguan.unizar.es/record/131363/files/texto_completo.pdf Postprint 1303941 http://zaguan.unizar.es/record/131363/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:131363 articulos driver 2024-02-08-10:05:59 ARTICLE