131452 20250702132815.0 doi 10.22489/CinC.2023.408 sideral 136867 ART-2023-136867 eng Gómez Fonseca, Neurys Universidad de Zaragoza (orcid)0000-0003-4078-5968 Changes in T-peak-to-T-end Morphology Measured by Time-Warping Are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model 2023 Access copy available to the general public Unrestricted In this work, we use a time-warping-based morphology variation index, dw , computed between the peak and the end of the T-wave, and assess its association with the occurrence of ventricular fibrillation (VF) episodes in ischemic conditions. ECG recordings from 26 pigs under- going a 40-minute coronary occlusion were analyzed. The dw series was obtained by quantifying the morphological differences between the final part of the T wave at different stages of the occlusion and a reference T wave in the control recording. During control recordings, dw remained stationary with a median value along each recording of 1.76 ms, IQR of 1.80, while during artery occlusion followed a well-marked gradual increasing trend as ischemia progressed, with median of 15.47 ms, IQR of 18.53. At the 20-to-25 min period from occlusion onset (and during 5 min prior to VF episode) d w averages in the VF group was significantly higher than in the non-VF group with median values of 40.0 (and 34.4) vs 7.8 (and 7.7) ms, with p-values of 0.002 (and 0.001), respectively. In conclusion, dynamic increases of the dw index during ischaemia progression in pigs are associated with VF occurrence. info:eu-repo/grantAgreement/ES/AEI/PID2021-128972OA-I00 info:eu-repo/grantAgreement/ES/DGA-FSE/T39-20R info:eu-repo/grantAgreement/ES/DGA/LMP141-21 info:eu-repo/grantAgreement/ES/MICINN/PID2019-104881RB-I00 info:eu-repo/grantAgreement/ES/MICINN/PID2019-105674RB-I00 info:eu-repo/grantAgreement/ES/MICINN/RYC2021-031413-I info:eu-repo/grantAgreement/EUR/MICINN/TED2021-130459B-I00 info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 0.227 2023 Computer Science (miscellaneous) 2023 Cardiology and Cardiovascular Medicine 2023 1.1 2023 info:eu-repo/semantics/conferenceObject info:eu-repo/semantics/acceptedVersion Ramírez, Julia Universidad de Zaragoza (orcid)0000-0003-4130-5866 Martin-Yebra, Alba Universidad de Zaragoza (orcid)0000-0003-0226-4950 M. Demidova, Marina Platonov, Pyotr Martínez, Juan Pablo Universidad de Zaragoza (orcid)0000-0002-7503-3339 Laguna, Pablo Universidad de Zaragoza (orcid)0000-0003-3434-9254 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. 50 (2023), [4 pp.] Comput. cardiol. Computing in Cardiology 2325-8861 376534 http://zaguan.unizar.es/record/131452/files/texto_completo.pdf Postprint 2699150 http://zaguan.unizar.es/record/131452/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:131452 articulos driver 2025-07-02-13:26:06 ARTICLE