000131456 001__ 131456
000131456 005__ 20240319081019.0
000131456 0247_ $$2doi$$a10.1007/s00423-022-02593-7
000131456 0248_ $$2sideral$$a129946
000131456 037__ $$aART-2022-129946
000131456 041__ $$aeng
000131456 100__ $$aGascón, María A.$$uUniversidad de Zaragoza
000131456 245__ $$aLocal full-thickness excision for sessile adenoma and cT1-2 rectal cancer: long-term oncological outcome
000131456 260__ $$c2022
000131456 5060_ $$aAccess copy available to the general public$$fUnrestricted
000131456 5203_ $$aPurpose: We analyzed all patients who underwent local transanal surgery at our institution to determine oncological outcomes and perioperative risk. Methods: In 1997, we developed a prospective protocol for rectal tumors: transanal local full-thickness excision was considered curative in patients with benign adenoma and early cancers. In this analysis, 404 patients were included. To analyze survival, only those patients exposed to the risk of dying for at least 5 years were considered for the study. Results: The final pathological analysis revealed that 262 (64.8%) patients had benign lesions, whereas 142 had malignant lesions. Postoperative complications were recorded in 12.6%. At the median time of 21 months, 14% of the adenomas and 12% of cancers had recurred, half of which were surgically resected. The overall 5-year survival rate was 94%. Conclusion. With similar outcomes and significantly lower morbidity, we found local surgery to be an adequate alternative to radical surgery in selected cases of early rectal cancer.
000131456 536__ $$9info:eu-repo/grantAgreement/ES/MISAN/FIS/01-0186$$9info:eu-repo/grantAgreement/ES/MISAN/FIS/98-0788
000131456 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000131456 590__ $$a2.3$$b2022
000131456 591__ $$aSURGERY$$b97 / 213 = 0.455$$c2022$$dQ2$$eT2
000131456 594__ $$a3.1$$b2022
000131456 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000131456 700__ $$0(orcid)0000-0001-5323-2946$$aAguilella, Vicente$$uUniversidad de Zaragoza
000131456 700__ $$0(orcid)0000-0002-9699-5289$$aMartínez, Tomás$$uUniversidad de Zaragoza
000131456 700__ $$0(orcid)0000-0002-7947-8781$$aAntinolfi, Luigi$$uUniversidad de Zaragoza
000131456 700__ $$0(orcid)0000-0002-0557-7015$$aValencia, Javier$$uUniversidad de Zaragoza
000131456 700__ $$0(orcid)0000-0001-7964-1166$$aRamírez, José M.$$uUniversidad de Zaragoza
000131456 7102_ $$11011$$2770$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Radiol. y Medicina Física
000131456 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000131456 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000131456 773__ $$g407 (2022), 2431–2439$$pLangenbeck's arch. surg.$$tLANGENBECKS ARCHIVES OF SURGERY$$x1435-2443
000131456 8564_ $$s912214$$uhttps://zaguan.unizar.es/record/131456/files/texto_completo.pdf$$yVersión publicada
000131456 8564_ $$s2273050$$uhttps://zaguan.unizar.es/record/131456/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000131456 909CO $$ooai:zaguan.unizar.es:131456$$particulos$$pdriver
000131456 951__ $$a2024-03-18-16:00:10
000131456 980__ $$aARTICLE