000131491 001__ 131491
000131491 005__ 20240209155916.0
000131491 0247_ $$2doi$$a10.1016/j.jpainsymman.2019.10.013
000131491 0248_ $$2sideral$$a136421
000131491 037__ $$aART-2020-136421
000131491 041__ $$aeng
000131491 100__ $$0(orcid)0000-0002-3132-2171$$aDíez-Manglano, Jesús$$uUniversidad de Zaragoza
000131491 245__ $$aPalliative Sedation in Patients Hospitalized in Internal Medicine Departments
000131491 260__ $$c2020
000131491 5060_ $$aAccess copy available to the general public$$fUnrestricted
000131491 5203_ $$aContext
Palliative sedation is used to relieve end-of-life refractory symptoms.
Objective
The objective of this study was to describe the use of palliative sedation in patients who die in internal medicine departments.
Methods
An observational, cross-sectional, retrospective, and multicenter clinical audit study was conducted in 145 hospitals in Spain and Argentina. Each hospital included the first 10 patients who died in the internal medicine department, starting on December 1, 2015.
Results
We included 1447 patients, and palliative sedation was administered to 701 patients (48.4%). Having a terminal illness (odds ratio [OR] 2.469, 95% CI 1.971–3.093, P < 0.001) and the length of hospital stay (OR 1.011, 95% CI 1.002–1.021, P = 0.017) were independently associated with the use of palliative sedation. Consent was granted by the families of 582 (83%) patients. The most common refractory symptom was dyspnea, and the most commonly used drugs for sedation were midazolam (77%) and morphine (89.7%). An induction dose was administered in 25.7% of the patients. Rescue doses were scheduled for 70% of the patients, and hydration was maintained in 49.5%. Pain was more common in patients with cancer, whereas dyspnea was more common in those without cancer. Rescue doses were used more often for the patients with cancer (77.8% vs. 67.7%, P = 0.015). Monitoring the palliative sedation with a scale was more frequent in the patients with cancer (23.7% vs. 14.3%, P = 0.008).
Conclusions
Palliative sedation is used more often for terminal patients. There are differences in the administration of palliative sedation between patients with and without cancer.
000131491 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000131491 590__ $$a3.612$$b2020
000131491 591__ $$aCLINICAL NEUROLOGY$$b85 / 208 = 0.409$$c2020$$dQ2$$eT2
000131491 591__ $$aMEDICINE, GENERAL & INTERNAL$$b47 / 167 = 0.281$$c2020$$dQ2$$eT1
000131491 591__ $$aHEALTH CARE SCIENCES & SERVICES$$b33 / 107 = 0.308$$c2020$$dQ2$$eT1
000131491 592__ $$a1.437$$b2020
000131491 593__ $$aAnesthesiology and Pain Medicine$$c2020$$dQ1
000131491 593__ $$aNursing (miscellaneous)$$c2020$$dQ1
000131491 593__ $$aNeurology (clinical)$$c2020$$dQ1
000131491 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000131491 700__ $$aIsasi de Isasmendi Pérez, Soledad
000131491 700__ $$aGarcía Fenoll, Rosa$$uUniversidad de Zaragoza
000131491 700__ $$aSánchez, Luis Ángel
000131491 700__ $$aFormiga, Françesc
000131491 700__ $$aGiner Galvañ, Vicente
000131491 700__ $$aDueñas, Carlos
000131491 700__ $$aRoca, Bernardino
000131491 700__ $$aEstrada Díaz, Cristina
000131491 700__ $$aCasariego Vales, Emilio
000131491 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000131491 773__ $$g59, 2 (2020), 302-309$$pJ. Pain Symptom Manage.$$tJOURNAL OF PAIN AND SYMPTOM MANAGEMENT$$x0885-3924
000131491 8564_ $$s429192$$uhttps://zaguan.unizar.es/record/131491/files/texto_completo.pdf$$yPostprint
000131491 8564_ $$s1732369$$uhttps://zaguan.unizar.es/record/131491/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000131491 909CO $$ooai:zaguan.unizar.es:131491$$particulos$$pdriver
000131491 951__ $$a2024-02-09-14:31:44
000131491 980__ $$aARTICLE