131491 20240209155916.0 doi 10.1016/j.jpainsymman.2019.10.013 sideral 136421 ART-2020-136421 eng Díez-Manglano, Jesús Universidad de Zaragoza (orcid)0000-0002-3132-2171 Palliative Sedation in Patients Hospitalized in Internal Medicine Departments 2020 Context Palliative sedation is used to relieve end-of-life refractory symptoms. Objective The objective of this study was to describe the use of palliative sedation in patients who die in internal medicine departments. Methods An observational, cross-sectional, retrospective, and multicenter clinical audit study was conducted in 145 hospitals in Spain and Argentina. Each hospital included the first 10 patients who died in the internal medicine department, starting on December 1, 2015. Results We included 1447 patients, and palliative sedation was administered to 701 patients (48.4%). Having a terminal illness (odds ratio [OR] 2.469, 95% CI 1.971–3.093, P < 0.001) and the length of hospital stay (OR 1.011, 95% CI 1.002–1.021, P = 0.017) were independently associated with the use of palliative sedation. Consent was granted by the families of 582 (83%) patients. The most common refractory symptom was dyspnea, and the most commonly used drugs for sedation were midazolam (77%) and morphine (89.7%). An induction dose was administered in 25.7% of the patients. Rescue doses were scheduled for 70% of the patients, and hydration was maintained in 49.5%. Pain was more common in patients with cancer, whereas dyspnea was more common in those without cancer. Rescue doses were used more often for the patients with cancer (77.8% vs. 67.7%, P = 0.015). Monitoring the palliative sedation with a scale was more frequent in the patients with cancer (23.7% vs. 14.3%, P = 0.008). Conclusions Palliative sedation is used more often for terminal patients. There are differences in the administration of palliative sedation between patients with and without cancer. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 3.612 2020 CLINICAL NEUROLOGY 85 / 208 = 0.409 2020 Q2 T2 MEDICINE, GENERAL & INTERNAL 47 / 167 = 0.281 2020 Q2 T1 HEALTH CARE SCIENCES & SERVICES 33 / 107 = 0.308 2020 Q2 T1 1.437 2020 Anesthesiology and Pain Medicine 2020 Q1 Nursing (miscellaneous) 2020 Q1 Neurology (clinical) 2020 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Isasi de Isasmendi Pérez, Soledad García Fenoll, Rosa Universidad de Zaragoza Sánchez, Luis Ángel Formiga, Françesc Giner Galvañ, Vicente Dueñas, Carlos Roca, Bernardino Estrada Díaz, Cristina Casariego Vales, Emilio 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 59, 2 (2020), 302-309 J. Pain Symptom Manage. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT 0885-3924 429192 http://zaguan.unizar.es/record/131491/files/texto_completo.pdf Postprint 1732369 http://zaguan.unizar.es/record/131491/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:131491 articulos driver 2024-02-09-14:31:44 ARTICLE