doi:10.1039/c5ja00157aengBolea-Fernandez, E.Balcaen, L.Resano, M.Vanhaecke, F.Tandem ICP-mass spectrometry for Sr isotopic analysis without prior Rb/Sr separationART-2016-93139The use of a mixture of 10% of CH3F and 90% of He as a reaction gas in tandem ICP-mass spectrometry (ICP-MS/MS) enables the accurate determination of the 87Sr/86Sr isotope ratio in geological materials, provided that mass discrimination is corrected for by using a combination of internal (Russell law, assuming a constant 88Sr/86Sr isotope ratio) and external correction (using the isotopic reference material NIST SRM 987 SrCO3) in a sample-standard bracketing approach. No prior Rb/Sr separation is required as the isobaric overlap at a mass-to-charge ratio of 87 is avoided by monitoring SrF+ reaction product ions instead of Sr+ ions. Rb shows no reactivity towards CH3F. The double mass selection (MS/MS mode) prevents both spectral overlap from atomic ions at the mass-to-charge ratios of SrF+ reaction product ions and a measurable effect from the matrix on the 87Sr/86Sr result. This aspect is critical, as it enables accurate results to be obtained without the need for using a matrix-matched standard to correct for mass discrimination, in contrast to previous work with a quadrupole ICP-MS instrument with a CH3F/Ne-pressurized cell, in which the use of a matrix-matched standard was compulsory. The precision attainable-0.05% RSD external precision-suffices for making the newly developed method useful in a variety of applications.2016http://zaguan.unizar.es/record/13150810.1039/c5ja00157ahttp://zaguan.unizar.es/record/131508oai:zaguan.unizar.es:131508info:eu-repo/grantAgreement/ES/MINECO/CTQ2012-33494Journal of Analytical Atomic Spectrometry 31, 1 (2016), 303-310All rights reservedhttp://www.europeana.eu/rights/rr-f/info:eu-repo/semantics/openAccess