Dynamic Configuration on a Chiral-at-Rhodium Catalyst Featuring a Flexible Tetradentate Ligand
Resumen: The unique dynamic configuration of an enantioselective chiral‐at‐metal catalyst based on Rh(III) and a non‐chiral tetradentate ligand is described and resolved. At room temperature, the catalyst undergoes a dynamic configuration process leading to the formation of two interconvertible metal‐stereoisomers, remarkably without racemization. Density functional theory (DFT) calculations indicate that this metal‐isomerization proceeds via a concerted transition state, which features a trigonal bipyramidal geometry stabilized by the tetradentate ligand. Furthermore, the resolved enantiopure complex shows high catalytic enantioinduction in the Friedel‐Crafts reaction, achieving enantiomeric ratios as high as 99 : 1.
Idioma: Inglés
DOI: 10.1002/chem.202303935
Año: 2024
Publicado en: Chemistry - A European Journal 30, 10 (2024), 202303935 [6 pp.]
ISSN: 0947-6539

Factor impacto SCIMAGO: 1.058 - Chemistry (miscellaneous) (Q1) - Organic Chemistry (Q1) - Catalysis (Q2)

Financiación: info:eu-repo/grantAgreement/ES/DGA/E05-23R
Financiación: info:eu-repo/grantAgreement/ES/MCIU-AEI-FEDER/PID2021-122406NB-100
Financiación: info:eu-repo/grantAgreement/ES/MCIU/RED2018-102574-T
Financiación: info:eu-repo/grantAgreement/ES/MICINN/CTQ2018-095561-BI00
Tipo y forma: Article (PostPrint)
Área (Departamento): Área Química Inorgánica (Dpto. Química Inorgánica)

Rights Reserved All rights reserved by journal editor


Fecha de embargo : 2024-11-30
Exportado de SIDERAL (2024-07-11-08:52:27)


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