000131783 001__ 131783
000131783 005__ 20241125101202.0
000131783 0247_ $$2doi$$a10.1186/s13071-023-06046-y
000131783 0248_ $$2sideral$$a137180
000131783 037__ $$aART-2023-137180
000131783 041__ $$aeng
000131783 100__ $$0(orcid)0000-0001-6209-4282$$aVillanueva-Saz, Sergio$$uUniversidad de Zaragoza
000131783 245__ $$aMolecular survey on vector-borne pathogens in clinically healthy stray cats in Zaragoza (Spain)
000131783 260__ $$c2023
000131783 5060_ $$aAccess copy available to the general public$$fUnrestricted
000131783 5203_ $$aBackground
In Europe, feline vector-borne infections are gaining importance because of the changing climate, expanding habitats of potential vectors and expanding pathogen reservoirs. The main objective of this study was to assess the prevalence of vector-borne pathogens (VBPs) in stray cats in Zaragoza, Spain, and to investigate potential risk factors for infection, including feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV).
Methods
Blood samples from stray cats presented to the veterinary faculty in Zaragoza between February 2020 and 2022 were tested by polymerase chain reaction (PCR) for the presence of Anaplasma phagocytophilum, Anaplasma platys, Bartonella henselae, Ehrlichia canis, Rickettsia spp., haemotropic Mycoplasma spp., Hepatozoon spp., Leishmania infantum, piroplasms and microfilariae at the LABOKLIN laboratory. The cats were also tested for FeLV and FIV by PCR.
Results
Nearly half of the cats (158/332, 47.6%) were positive for at least one VBP. Hepatozoon spp. were detected in 25.6%, haemotropic Mycoplasma spp. in 22.9%, B. henselae in 9.3% and L. infantum in 2.1% of the cats. Male sex had a statistically significant association with test results for haemotropic Mycoplasma spp. (odds ratio 1.38 [1.21;1.57]); regionality with Hepatozoon spp., B. henseale and FIV; and seasonality with Hepatozoon spp., haemotropic Mycoplasma spp., L. infantum and FeLV (P ≤ 0.05 each). A strong positive correlation was reported for the amount of rainfall and the number of cats that tested positive for Hepatozoon spp. (ρ = 753, P = 0.05). None of the cats tested positive for A. phagocytophilum, A. platys, E. canis, Rickettsia spp., piroplasms, or microfilariae. Co-infections with multiple VBPs were detected in 56 out of 332 cats (16.9%). Thirty-one of the 332 cats included in the study (9.3%) tested positive for FeLV (6.9%) and for FIV (3.6%). In 20/31 cats (64.5%) that tested positive for FeLV/FIV, coinfections with VBP were detected (P = 0.048, OR 2.15 [0.99; 4.64]).
Conclusions
VBPs were frequently detected in stray cats in Zaragoza. In particular, regionality and seasonality had a statistically significant association with PCR results for most VBPs included in the study.
000131783 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000131783 590__ $$a3.0$$b2023
000131783 592__ $$a0.967$$b2023
000131783 591__ $$aTROPICAL MEDICINE$$b6 / 28 = 0.214$$c2023$$dQ1$$eT1
000131783 593__ $$aParasitology$$c2023$$dQ1
000131783 591__ $$aPARASITOLOGY$$b11 / 45 = 0.244$$c2023$$dQ1$$eT1
000131783 593__ $$aInfectious Diseases$$c2023$$dQ1
000131783 594__ $$a6.3$$b2023
000131783 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000131783 700__ $$aMartínez, Marivi
000131783 700__ $$aNijhof, Ard M.
000131783 700__ $$aGerst, Bastian
000131783 700__ $$aGentil, Michaela
000131783 700__ $$aMüller, Elisabeth
000131783 700__ $$0(orcid)0000-0002-2557-4890$$aFernández, Antonio$$uUniversidad de Zaragoza
000131783 700__ $$aGonzález, Ana
000131783 700__ $$aYusuf, Mohamed Sh. Mohamud
000131783 700__ $$aGreco, Grazia
000131783 700__ $$0(orcid)0000-0003-2957-1379$$aVerde, Maite$$uUniversidad de Zaragoza
000131783 700__ $$aSgroi, Giovanni
000131783 700__ $$0(orcid)0000-0002-7822-6646$$aLacasta, Delia$$uUniversidad de Zaragoza
000131783 700__ $$aMarteles, Diana
000131783 700__ $$aTrotta, Michele
000131783 700__ $$aSchäfer, Ingo
000131783 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000131783 773__ $$g16, 1 (2023), [11 pp.]$$pParasit. vectors$$tParasites & vectors$$x1756-3305
000131783 8564_ $$s975863$$uhttps://zaguan.unizar.es/record/131783/files/texto_completo.pdf$$yVersión publicada
000131783 8564_ $$s2218503$$uhttps://zaguan.unizar.es/record/131783/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000131783 909CO $$ooai:zaguan.unizar.es:131783$$particulos$$pdriver
000131783 951__ $$a2024-11-22-12:12:06
000131783 980__ $$aARTICLE