000131861 001__ 131861
000131861 005__ 20241125101203.0
000131861 0247_ $$2doi$$a10.3389/fpubh.2023.1309094
000131861 0248_ $$2sideral$$a137252
000131861 037__ $$aART-2023-137252
000131861 041__ $$aeng
000131861 100__ $$aQuintana-Diaz, Manuel
000131861 245__ $$a"COAGULATION": a mnemonic device for treating coagulation disorders following traumatic brain injury—a narrative-based method in the intensive care unit
000131861 260__ $$c2023
000131861 5060_ $$aAccess copy available to the general public$$fUnrestricted
000131861 5203_ $$aIntroductionCoagulopathy associated with isolated traumatic brain injury (C-iTBI) is a frequent complication associated with poor outcomes, primarily due to its role in the development or progression of haemorrhagic brain lesions. The independent risk factors for its onset are age, severity of traumatic brain injury (TBI), volume of fluids administered during resuscitation, and pre-injury use of antithrombotic drugs. Although the pathophysiology of C-iTBI has not been fully elucidated, two distinct stages have been identified: an initial hypocoagulable phase that begins within the first 24 h, dominated by platelet dysfunction and hyperfibrinolysis, followed by a hypercoagulable state that generally starts 72 h after the trauma. The aim of this study was to design an acronym as a mnemonic device to provide clinicians with an auxiliary tool in the treatment of this complication.MethodsA narrative analysis was performed in which intensive care physicians were asked to list the key factors related to C-iTBI. The initial sample was comprised of 33 respondents. Respondents who were not physicians, not currently working in or with experience in coagulopathy were excluded. Interviews were conducted for a month until the sample was saturated. Each participant was asked a single question: Can you identify a factor associated with coagulopathy in patients with TBI? Factors identified by respondents were then submitted to a quality check based on published studies and proven evidence. Because all the factors identified had strong support in the literature, none was eliminated. An acronym was then developed to create the mnemonic device.Results and conclusionEleven factors were identified: cerebral computed tomography, oral anticoagulant & antiplatelet use, arterial blood pressure (Hypotension), goal-directed haemostatic therapy, use fluids cautiously, low calcium levels, anaemia-transfusion, temperature, international normalised ratio (INR), oral antithrombotic reversal, normal acid–base status, forming the acronym “Coagulation.” This acronym is a simple mnemonic device, easy to apply for anyone facing the challenge of treating patients of moderate or severe TBI on a daily basis.
000131861 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000131861 590__ $$a3.0$$b2023
000131861 592__ $$a0.895$$b2023
000131861 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b115 / 408 = 0.282$$c2023$$dQ2$$eT1
000131861 593__ $$aPublic Health, Environmental and Occupational Health$$c2023$$dQ1
000131861 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b115 / 408 = 0.282$$c2023$$dQ2$$eT1
000131861 594__ $$a4.8$$b2023
000131861 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000131861 700__ $$aAnania, Pasquale
000131861 700__ $$aJuárez-Vela, Raúl
000131861 700__ $$0(orcid)0000-0002-4753-630X$$aEchaniz-Serrano, Emmanuel$$uUniversidad de Zaragoza
000131861 700__ $$aTejada-Garrido, Clara Isabel
000131861 700__ $$aSanchez-Conde, Pilar
000131861 700__ $$aNanwani-Nanwani, Kapil
000131861 700__ $$aSerrano-Lázaro, Ainhoa
000131861 700__ $$aMarcos-Neira, Pilar
000131861 700__ $$aGero-Escapa, María
000131861 700__ $$aGarcía-Criado, Jorge
000131861 700__ $$aGodoy, Daniel Agustín
000131861 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000131861 773__ $$g11 (2023), 1309094 [12 pp.]$$pFront. public health.$$tFrontiers in public health$$x2296-2565
000131861 8564_ $$s868418$$uhttps://zaguan.unizar.es/record/131861/files/texto_completo.pdf$$yVersión publicada
000131861 8564_ $$s2404022$$uhttps://zaguan.unizar.es/record/131861/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000131861 909CO $$ooai:zaguan.unizar.es:131861$$particulos$$pdriver
000131861 951__ $$a2024-11-22-12:12:31
000131861 980__ $$aARTICLE