131894 20240731103415.0 doi 10.1177/20552173231169475 sideral 137002 ART-2023-137002 eng Sainz de la Maza, Susana Detecting disability using self-reported and clinical assessments in early-stage relapsing-remitting multiple sclerosis: Looking for a complementary approach 2023 Access copy available to the general public Unrestricted Disability accrual is mainly driven by progression independent of relapse activity, which is present even in early stages of relapsing-remitting multiple sclerosis (RRMS) and sometimes overlooked. This multicenter, non-interventional study evaluated whether patient-reported outcomes measures (PROMs) could capture disability in 189 early-stage RRMS patients (mean age: 36.1 ± 9.4 years, 71.4% female, mean disease duration: 1.4 ± 0.8 years, median EDSS: 1.0). The 9-Hole Peg Test (9-HPT), NeuroQoL Upper Extremity (NeuroQoL-UE), Timed 25-Foot Walk (T25-FW), Multiple Sclerosis Walking Scale (MSWS-12), Symbol Digit Modalities Test (SDMT), and Perceived Deficits Questionnaire (PDQ-5) were used to assess hand function, gait, and cognition, respectively. These functions were at least mildly affected in this early-stage population, finding significant correlations between PROMs and clinical assessments. PROMs could enable early-stage RRMS patients to communicate their perceived disability in different domains, assisting clinicians in disease monitoring and decision making. info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 0.959 2023 Neurology (clinical) 2023 Q2 Cellular and Molecular Neuroscience 2023 Q3 4.7 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Gómez-Ballesteros, Rocío Borges, Mónica Martín-Martínez, Jesús Sotoca, Javier Alonso, Ana Caminero, Ana B. Borrega, Laura Sánchez-Menoyo, José L. Barrero-Hernández, Francisco J. Calles, Carmen Brieva, Luis Blasco-Quílez, María R. Dotor García-Soto, Julio Campo-Amigo, María del Navarro-Cantó, Laura Agüera, Eduardo Garcés-Redondo, Moisés Universidad de Zaragoza (orcid)0000-0002-1756-5492 Carmona, Olga Gabaldón-Torres, Laura Forero, Lucía Hervàs, Mariona Medrano, Nicolás Maurino, Jorge Castillo-Triviño, Tamara 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 9, 2 (2023), [7 pp.] Multiple Sclerosis Journal - Experimental, Translational and Clinical 2055-2173 744576 http://zaguan.unizar.es/record/131894/files/texto_completo.pdf Versión publicada 2595322 http://zaguan.unizar.es/record/131894/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:131894 articulos driver 2024-07-31-10:06:19 ARTICLE