000131897 001__ 131897
000131897 005__ 20240219150723.0
000131897 0247_ $$2doi$$a10.1016/j.ijregi.2023.11.010
000131897 0248_ $$2sideral$$a137165
000131897 037__ $$aART-2024-137165
000131897 041__ $$aeng
000131897 100__ $$aEncinas, Begoña
000131897 245__ $$aHTLV-1 infection among Latin American pregnant women living in Spain
000131897 260__ $$c2024
000131897 5060_ $$aAccess copy available to the general public$$fUnrestricted
000131897 5203_ $$aObjectives
Human T-lymphotropic virus (HTLV) antenatal screening is not mandatory in Spain. Surveys conducted decades ago reported HTLV-1 seroprevalence rates of 0.2% among foreign pregnant women in Spain. The migrant flow to Spain from HTLV-1 endemic regions in Latin America and sub-Saharan Africa has increased during the last decade. Currently, 25% of pregnant women in Spain are foreigners.
Methods
From January 2021 to October 2023 a cross-sectional study was carried out in all consecutive pregnant women attended at eleven Spanish clinics. A commercial enzyme immunoassay (EIA) was used for screening of serum HTLV-1/2 antibodies. Reactive samples were confirmed by immunoblot.
Results
A total of 9813 pregnant women with a median age of 34 years-old were examined. Native Spaniards were 6977 (76.5%). Of 2147 foreigners (23.5%), 903566 (9.9%) were Latin Americans, 416 (4.5%) North Africans, 293 (3.2%) from Romania, and 196 (2.1%) from sub-Saharan Africa. A total of 47 samples were EIA reactive but only five were confirmed as HTLV-1 positive using immunoblot. Infected women came from Paraguay, Colombia, the Dominican Republic, Venezuela and Peru. All but one were primigravida, with ages ranging from 20 to 33 years-old. One was HIV-1 positive, and another was infected with Chlamydia trachomatis.
Conclusion
The overall seroprevalence for HTLV-1 among pregnant women in Spain is 0.05% but rises ten-fold (0.55%) among Latin Americans. This rate is higher than in surveys conducted decades ago. Our results support that anti-HTLV testing should be part of antenatal screening in Spain in pregnant women coming from Latin America, as it is already done with Chagas disease.
000131897 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI21-1717
000131897 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000131897 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000131897 700__ $$0(orcid)0000-0001-5134-1006$$aBenito, Rafael$$uUniversidad de Zaragoza
000131897 700__ $$aRojo, Silvia
000131897 700__ $$aReina, Gabriel
000131897 700__ $$aMontiel, Natalia
000131897 700__ $$aAguilera, Antonio
000131897 700__ $$aEiros, José María
000131897 700__ $$aGarcía-Costa, Juan
000131897 700__ $$aOrtega, Diego$$uUniversidad de Zaragoza
000131897 700__ $$aArco, Irene
000131897 700__ $$aHernánez-Batancor, Araceli
000131897 700__ $$aSoriano, Vicente
000131897 700__ $$ade-Mendoza, Carmen
000131897 700__ $$aCalderón, E.
000131897 700__ $$aRodríguez-Iglesias, M.
000131897 700__ $$aTrujillo, T.
000131897 700__ $$aViciana, Cádiz I.
000131897 700__ $$aCabezas, Málaga T.
000131897 700__ $$aLozano, Almería A.
000131897 700__ $$aFernández-Fuertes, E.
000131897 700__ $$aFernández, J.M.
000131897 700__ $$aGarcía, F.
000131897 700__ $$0(orcid)0000-0002-0036-6630$$aAlgarate, S.
000131897 700__ $$aDucons, M.
000131897 700__ $$aRoc, L.
000131897 700__ $$aCifuentes, C.
000131897 700__ $$aFernández-Baca, V.
000131897 700__ $$aFernández-Montero, J.V
000131897 700__ $$aMaciá, M.D.
000131897 700__ $$aHernández-Betancor, A.
000131897 700__ $$aMartín, A.M.
000131897 700__ $$aPena, M.J.
000131897 700__ $$aHernández, M.
000131897 700__ $$aLópez-Lirola, A.M.
000131897 700__ $$aGómez-Sirvent, J.L.
000131897 700__ $$aCopado, R.
000131897 700__ $$aCano, M.E.
000131897 700__ $$aEirós, J.M.
000131897 700__ $$aRodríguez, M.
000131897 700__ $$aGómez-Hernando, C.
000131897 700__ $$aGonzález-Praetorius, A.
000131897 700__ $$aRando, A.
000131897 700__ $$aForce, L.
000131897 700__ $$aMiró, E.
000131897 700__ $$aCebollero, A.
000131897 700__ $$aDelgado, J.F.
000131897 700__ $$aRodríguez, G.
000131897 700__ $$aFernández-Pereira, L.
000131897 700__ $$aPereira, S.
000131897 700__ $$aGarcía, J.
000131897 700__ $$aArcay, R.
000131897 700__ $$aTrigo, M.
000131897 700__ $$aDiz, J.
000131897 700__ $$aGarcía-Campello, M.
000131897 700__ $$aCortizo, S.
000131897 700__ $$aPérez, S.
000131897 700__ $$aMorano, L.
000131897 700__ $$aArazamendi, M.
000131897 700__ $$aSalicio, Y.
000131897 700__ $$aUgalde, E.
000131897 700__ $$aNieto, M.C.
000131897 700__ $$aLiendo, P.
000131897 700__ $$aGoikoetxea, A.J.
000131897 700__ $$aOcete, M.D.
000131897 700__ $$aRamos, J.M.
000131897 700__ $$aEscribano, I.
000131897 700__ $$aSauleda, S.
000131897 700__ $$aPirón, M.
000131897 700__ $$aGonzález, R.
000131897 700__ $$aRichart, A.
000131897 700__ $$aBarea, L.
000131897 700__ $$aJiménez, A.
000131897 700__ $$aBlanco, L.
000131897 700__ $$aNavarro, L.
000131897 700__ $$aAyerdi, O.
000131897 700__ $$aBaza, B.
000131897 700__ $$aRodriguez, C.
000131897 700__ $$adel-Romero, J.
000131897 700__ $$aGalar, A.
000131897 700__ $$aAldamiz, T.
000131897 700__ $$aValeiro, M.
000131897 700__ $$aPérez, L.
000131897 700__ $$aRodríguez-Avial, I.
000131897 700__ $$aMartín-Carbonero, L.
000131897 700__ $$aFernández-Ruiz, M.
000131897 700__ $$aParra, P.
000131897 700__ $$aRedondo, N.
000131897 700__ $$aRuiz-Merlo, T.
000131897 700__ $$aPozuelo, M.J.
000131897 700__ $$aBarreiro, P.
000131897 700__ $$aTreviño, A.
000131897 700__ $$ade-Jesús, F.
000131897 700__ $$aCorral, O.
000131897 700__ $$aPintos, I.
000131897 700__ $$aMoreno-Torres, V.
000131897 700__ $$aCarrizo, P.
000131897 700__ $$aHuertas, A.
000131897 700__ $$aVargas-Núñez, J.A.
000131897 7102_ $$11011$$2630$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Microbiología
000131897 773__ $$g10 (2024), 146-149$$pIJID reg.$$tIJID regions$$x2772-7076
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000131897 951__ $$a2024-02-19-13:29:47
000131897 980__ $$aARTICLE