doi:10.1016/j.ijregi.2023.11.010engEncinas, BegoñaBenito, RafaelRojo, SilviaReina, GabrielMontiel, NataliaAguilera, AntonioEiros, José MaríaGarcía-Costa, JuanOrtega, DiegoArco, IreneHernánez-Batancor, AraceliSoriano, Vicentede-Mendoza, CarmenCalderón, E.Rodríguez-Iglesias, M.Trujillo, T.Viciana, Cádiz I.Cabezas, Málaga T.Lozano, Almería A.Fernández-Fuertes, E.Fernández, J.M.García, F.Algarate, S.Ducons, M.Roc, L.Cifuentes, C.Fernández-Baca, V.Fernández-Montero, J.VMaciá, M.D.Hernández-Betancor, A.Martín, A.M.Pena, M.J.Hernández, M.López-Lirola, A.M.Gómez-Sirvent, J.L.Copado, R.Cano, M.E.Eirós, J.M.Rodríguez, M.Gómez-Hernando, C.González-Praetorius, A.Rando, A.Force, L.Miró, E.Cebollero, A.Delgado, J.F.Rodríguez, G.Fernández-Pereira, L.Pereira, S.García, J.Arcay, R.Trigo, M.Diz, J.García-Campello, M.Cortizo, S.Pérez, S.Morano, L.Arazamendi, M.Salicio, Y.Ugalde, E.Nieto, M.C.Liendo, P.Goikoetxea, A.J.Ocete, M.D.Ramos, J.M.Escribano, I.Sauleda, S.Pirón, M.González, R.Richart, A.Barea, L.Jiménez, A.Blanco, L.Navarro, L.Ayerdi, O.Baza, B.Rodriguez, C.del-Romero, J.Galar, A.Aldamiz, T.Valeiro, M.Pérez, L.Rodríguez-Avial, I.Martín-Carbonero, L.Fernández-Ruiz, M.Parra, P.Redondo, N.Ruiz-Merlo, T.Pozuelo, M.J.Barreiro, P.Treviño, A.de-Jesús, F.Corral, O.Pintos, I.Moreno-Torres, V.Carrizo, P.Huertas, A.Vargas-Núñez, J.A.HTLV-1 infection among Latin American pregnant women living in SpainART-2024-137165Objectives. Human T-lymphotropic virus (HTLV) antenatal screening is not mandatory in Spain. Surveys conducted decades ago reported HTLV-1 seroprevalence rates of 0.2% among foreign pregnant women in Spain. The migrant flow to Spain from HTLV-1 endemic regions in Latin America and sub-Saharan Africa has increased during the last decade. Currently, 25% of pregnant women in Spain are foreigners. Methods. From January 2021 to October 2023 a cross-sectional study was carried out in all consecutive pregnant women attended at eleven Spanish clinics. A commercial enzyme immunoassay (EIA) was used for screening of serum HTLV-1/2 antibodies. Reactive samples were confirmed by immunoblot. Results. A total of 9813 pregnant women with a median age of 34 years-old were examined. Native Spaniards were 6977 (76.5%). Of 2147 foreigners (23.5%), 903566 (9.9%) were Latin Americans, 416 (4.5%) North Africans, 293 (3.2%) from Romania, and 196 (2.1%) from sub-Saharan Africa. A total of 47 samples were EIA reactive but only five were confirmed as HTLV-1 positive using immunoblot. Infected women came from Paraguay, Colombia, the Dominican Republic, Venezuela and Peru. All but one were primigravida, with ages ranging from 20 to 33 years-old. One was HIV-1 positive, and another was infected with Chlamydia trachomatis. Conclusion. The overall seroprevalence for HTLV-1 among pregnant women in Spain is 0.05% but rises ten-fold (0.55%) among Latin Americans. This rate is higher than in surveys conducted decades ago. Our results support that anti-HTLV testing should be part of antenatal screening in Spain in pregnant women coming from Latin America, as it is already done with Chagas disease.2024http://zaguan.unizar.es/record/13189710.1016/j.ijregi.2023.11.010http://zaguan.unizar.es/record/131897oai:zaguan.unizar.es:131897info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI21-1717IJID regions 10 (2024), 146-149byhttps://creativecommons.org/licenses/by/4.0/deed.esinfo:eu-repo/semantics/openAccess