132107 20240301161205.0 doi 10.1021/jacs.1c04115 sideral 131576 ART-2021-131576 eng Concellón, Alberto (orcid)0000-0002-8932-9085 Complex liquid crystal emulsions for biosensing 2021 Herein we describe a highly responsive optical biosensor based on dynamic complex liquid crystal (LC) emulsions. These emulsions are simple to prepare and consist of immiscible chiral nematic liquid crystals (N*) and fluorocarbon oils. In this work, we exploit the N* selective reflection to build a new sensing paradigm. Our detection strategy is based on changes in the LC/water interfacial activity of boronic acid polymeric surfactants caused by reversible interactions with IgG antibodies at the LC interface. Such biomolecular recognition events can vary the pitch length of the N* organization due to the presence of binaphthyl units in the polymeric structure, which are known to be powerful chiral dopants. We demonstrate that these interface-triggered reflection changes can be used as an effective optical read-out for the detection of the foodborne pathogen Salmonella. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 16.383 2021 CHEMISTRY, MULTIDISCIPLINARY 16 / 179 = 0.089 2021 Q1 T1 5.728 2021 Biochemistry 2021 Q1 Colloid and Surface Chemistry 2021 Q1 Catalysis 2021 Q1 25.2 2021 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Fong, Darryl Swager, Timothy M. 143, 24 (2021), 9177-9182 J. Am. Chem. Soc. Journal of the American Chemical Society 0002-7863 1241940 http://zaguan.unizar.es/record/132107/files/texto_completo.pdf Postprint 2917375 http://zaguan.unizar.es/record/132107/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:132107 articulos driver 2024-03-01-14:46:27 ARTICLE