000132119 001__ 132119
000132119 005__ 20240319081019.0
000132119 0247_ $$2doi$$a10.1039/d2gc01293f
000132119 0248_ $$2sideral$$a129944
000132119 037__ $$aART-2022-129944
000132119 041__ $$aeng
000132119 100__ $$aGarralaga, María Pilar
000132119 245__ $$aEcotoxicological study of bio-based deep eutectic solvents formed by glycerol derivatives in two aquatic biomodels
000132119 260__ $$c2022
000132119 5060_ $$aAccess copy available to the general public$$fUnrestricted
000132119 5203_ $$aThe growing environmental impact of non-renewable solvents has generated an increasing interest in the development of more sustainable alternatives. Among these options, deep eutectic solvents (DES) are attracting great interest. The favourable physicochemical properties of these solvents make them a potential green alternative for several applications. However, its toxicological impact has not been studied enough to assume the absence of environmental risk. With the main purpose of establishing an initial overview of the aquatic toxicity, an acute ecotoxicity test of different eutectic solvents, composed of glycerol or glycerol-derived ethers and choline chloride (ChCl) or N, N, N-triethyl-N-(2, 3-dihydroxypropyl)ammonium chloride (N00Cl), has been carried out in two aquatic biomodels: Aliivibrio fischeri (bacteria) and Raphidocelis subcapitata (algae). Furthermore, the content of chlorophyll was measured to observe the disruption of the photosynthetic process by the tested compounds. A dose-effect correlation has been observed, although very high concentrations of the solvents were necessary for the onset of the toxic effect. The toxicity of the DES, within the ChCl case, turned out to be greatly related to the polarizability and hydrophobicity of the solvents. Whereas N00Cl-based DES have shown an even-odd trend, compounds with even carbon numbers in the ether radical show lower toxicity than odd ones. These preliminary results point out a favourable eco-toxicological behaviour of glycerol derived DES, although studies in other bioindicators, as well as in cells and biodegradability tests are recommended in order to have a complete overview of the toxicological profiles of these promising solvents. © 2022 The Royal Society of Chemistry.
000132119 536__ $$9info:eu-repo/grantAgreement/ES/DGA-ERDF/E37-20R$$9info:eu-repo/grantAgreement/ES/DGA/E31-17R$$9info:eu-repo/grantAgreement/ES/MCIU/RTI2018-093431-B-I00
000132119 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000132119 590__ $$a9.8$$b2022
000132119 591__ $$aGREEN & SUSTAINABLE SCIENCE & TECHNOLOGY$$b9 / 46 = 0.196$$c2022$$dQ1$$eT1
000132119 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b24 / 178 = 0.135$$c2022$$dQ1$$eT1
000132119 592__ $$a1.959$$b2022
000132119 593__ $$aPollution$$c2022$$dQ1
000132119 593__ $$aEnvironmental Chemistry$$c2022$$dQ1
000132119 594__ $$a16.4$$b2022
000132119 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000132119 700__ $$aLomba, Laura
000132119 700__ $$0(orcid)0000-0002-3256-2089$$aLeal-Duaso, Alejandro$$uUniversidad de Zaragoza
000132119 700__ $$aGracia-Barberán, Sara
000132119 700__ $$0(orcid)0000-0002-2676-8814$$aPires, Elisabet$$uUniversidad de Zaragoza
000132119 700__ $$0(orcid)0000-0001-8669-2789$$aGiner, Beatriz
000132119 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000132119 773__ $$g24, 13 (2022), 5228–5241$$pGreen chem.$$tGREEN CHEMISTRY$$x1463-9262
000132119 8564_ $$s886380$$uhttps://zaguan.unizar.es/record/132119/files/texto_completo.pdf$$yPostprint
000132119 8564_ $$s805062$$uhttps://zaguan.unizar.es/record/132119/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000132119 909CO $$ooai:zaguan.unizar.es:132119$$particulos$$pdriver
000132119 951__ $$a2024-03-18-16:00:05
000132119 980__ $$aARTICLE