000132198 001__ 132198 000132198 005__ 20241125101142.0 000132198 0247_ $$2doi$$a10.1016/j.talanta.2023.124999 000132198 0248_ $$2sideral$$a137332 000132198 037__ $$aART-2023-137332 000132198 041__ $$aeng 000132198 100__ $$0(orcid)0000-0002-8765-4319$$aVera, Paula$$uUniversidad de Zaragoza 000132198 245__ $$aThe analysis of the migration of per and poly fluoroalkyl substances (PFAS) from food contact materials using ultrahigh performance liquid chromatography coupled to ion-mobility quadrupole time-of-flight mass spectrometry (UPLC- IMS-QTOF) 000132198 260__ $$c2023 000132198 5060_ $$aAccess copy available to the general public$$fUnrestricted 000132198 5203_ $$aPer-poly fluoroalkyl substances (PFASs) are a group of synthetic fluorine compounds used in food packaging materials to repel water and fats. This study assessed the chemical migration of PFAS from different food contact materials, including cardboard, recycled cardboard, biopolymer, paper and Teflon trays, from various markets. Migration assays were conducted using Tenax® as a food simulant, which was optimized by subjecting it to three consecutive extractions with 3 mL of ethanol within an hour. The resulting extractions were combined and concentrated to 0.5 mL using a nitrogen stream. The analysis was performed using ultrahigh performance liquid chromatography (UPLC) coupled with ion-mobility (IMS) quadrupole-time-of-flight (QTOF) mass spectrometry, which provided a powerful and novel tool for identifying a library of targets containing collision cross section values (CCS) and increasing confidence in subsequent identifications. Eleven PFAS compounds belonging to the family of perfluorocarboxylic acid, perfluorosulfonic acid and perfluorooctanesulfonamidoacetic acid substances (PFCAs, PFSAs and FOSAAs) were found in packaging samples obtained from China, with migrant concentrations ranging 3.2 and 22.3 μg/kg. In contrast, no detectable levels of PFAS were observed in packaging samples obtained in Spain. All trays tested were deemed to be suitable for use as food contact materials due to the fact that their migrant values were lower than 0.025 mg/kg for PFOA and its salts, and lower than a maximum concentration of 1 mg/kg for PFOA-related compounds. 000132198 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/T53-17R 000132198 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000132198 590__ $$a5.6$$b2023 000132198 592__ $$a0.956$$b2023 000132198 591__ $$aCHEMISTRY, ANALYTICAL$$b12 / 106 = 0.113$$c2023$$dQ1$$eT1 000132198 593__ $$aAnalytical Chemistry$$c2023$$dQ1 000132198 593__ $$aSpectroscopy$$c2023$$dQ1 000132198 593__ $$aBiochemistry$$c2023$$dQ2 000132198 594__ $$a12.3$$b2023 000132198 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000132198 700__ $$0(orcid)0000-0003-2638-9221$$aCanellas, Elena$$uUniversidad de Zaragoza 000132198 700__ $$aDreolin, Nicola 000132198 700__ $$aGoshawk, Jeff 000132198 700__ $$0(orcid)0000-0003-2685-5739$$aNerín, Cristina$$uUniversidad de Zaragoza 000132198 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica 000132198 773__ $$g266 (2023), 124999 [9 pp.]$$pTalanta$$tTalanta$$x0039-9140 000132198 8564_ $$s2800716$$uhttps://zaguan.unizar.es/record/132198/files/texto_completo.pdf$$yVersión publicada 000132198 8564_ $$s2492831$$uhttps://zaguan.unizar.es/record/132198/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000132198 909CO $$ooai:zaguan.unizar.es:132198$$particulos$$pdriver 000132198 951__ $$a2024-11-22-12:03:03 000132198 980__ $$aARTICLE