000132218 001__ 132218
000132218 005__ 20241125101142.0
000132218 0247_ $$2doi$$a10.3390/jcm13010211
000132218 0248_ $$2sideral$$a137433
000132218 037__ $$aART-2023-137433
000132218 041__ $$aeng
000132218 100__ $$0(orcid)0000-0003-2710-1875$$aOrduna-Hospital, Elvira$$uUniversidad de Zaragoza
000132218 245__ $$aAdaptive Illuminance Effects on Retinal Morphology and Refraction: A Comprehensive Study of Night Myopia
000132218 260__ $$c2023
000132218 5060_ $$aAccess copy available to the general public$$fUnrestricted
000132218 5203_ $$aBackground: We aimed to study the optical and retinal modifications that occur after adapting to different lighting conditions including photopic, mesopic, scotopic, blue light and red light conditions. Methods: Thirty young healthy subjects with a mean age of 23.57 ± 3.45 years were involved in the study (both eyes included). They underwent aberrometry and optical coherence tomography at both the central and peripheral retina with the 3 × 3 mm2 macular cube protocol before starting adaptation to the illuminations (baseline) and after remaining for 5 min under the five different lighting conditions inside a controlled lighting cabinet. Results: Significant myopization (p = 0.002) was observed under scotopic and mesopic lighting conditions, while hypermetropization occurred under the influence of blue LED light. In the central retina, a significant thickening of the inner temporal (p = 0.025) and outer inferior (p = 0.021) areas was observed in the scotopic area, and the thickening increased even more under blue and red light. The mean central thickness decreased significantly under photopic lighting conditions (p = 0.038). There was an increase in the mean volume of the central retinal area with red light and a reduction in the volume under photopic lighting (p = 0.039). In the peripheral retina, no significant thickness changes were observed after adapting to any of the lighting conditions (p > 0.05). Regarding morphological changes, a significant increase in retinal eccentricity (p = 0.045) and the shape factor (p = 0.036) was found. In addition, a significant correlation was found only between the eccentricity and volume of the central retina in scotopic conditions (r = −0.265; p = 0.041), meaning that a higher volume was associated with lower retinal eccentricity. Conclusions: When exposed to different lighting conditions, the retina changes in shape, and ocular refraction is modified to adapt to each condition, revealing the phenomenon of night myopia when transitioning from photopic to scotopic regimes.
000132218 536__ $$9info:eu-repo/grantAgreement/ES/DGA/LMP39_21$$9info:eu-repo/grantAgreement/EC/H2020/956720/EU/Opto-Biomechanical Eye Research Network/OBERON$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 956720-OBERON$$9info:eu-repo/grantAgreement/ES/MICINN/PID2019-107058RB-I00
000132218 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000132218 590__ $$a3.0$$b2023
000132218 592__ $$a0.882$$b2023
000132218 591__ $$aMEDICINE, GENERAL & INTERNAL$$b59 / 329 = 0.179$$c2023$$dQ1$$eT1
000132218 593__ $$aMedicine (miscellaneous)$$c2023$$dQ1
000132218 594__ $$a5.7$$b2023
000132218 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000132218 700__ $$aCrespo-Castan, Cynthia
000132218 700__ $$0(orcid)0000-0002-9068-7728$$aÁvila, Francisco J.$$uUniversidad de Zaragoza
000132218 700__ $$0(orcid)0000-0002-5621-1937$$aSanchez-Cano, Ana$$uUniversidad de Zaragoza
000132218 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000132218 773__ $$g13, 1 (2023), 211 [12 pp.]$$pJ. clin.med.$$tJournal of Clinical Medicine$$x2077-0383
000132218 8564_ $$s3832939$$uhttps://zaguan.unizar.es/record/132218/files/texto_completo.pdf$$yVersión publicada
000132218 8564_ $$s2748889$$uhttps://zaguan.unizar.es/record/132218/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000132218 909CO $$ooai:zaguan.unizar.es:132218$$particulos$$pdriver
000132218 951__ $$a2024-11-22-12:03:04
000132218 980__ $$aARTICLE