Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

Paz-Artigas, Laura González-Lana, Sandra Polo, Nicolás Vicente, Pedro Montero-Calle, Pilar Martínez, Miguel A. Rábago, Gregorio Serra, Margarida Prósper, Felipe Mazo, Manuel M. González, Arantxa Ochoa, Ignacio Ciriza, Jesús Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

ACS biomater. sci. eng.

10.1021/acsbiomaterials.3c01302 2024

2024