000132778 001__ 132778
000132778 005__ 20240315113107.0
000132778 0247_ $$2doi$$a10.1016/j.physbeh.2023.114451
000132778 0248_ $$2sideral$$a137695
000132778 037__ $$aART-2024-137695
000132778 041__ $$aeng
000132778 100__ $$aMeunier, Maxime A.
000132778 245__ $$aHair from sexually active bucks strongly activates olfactory sensory inputs but fails to trigger early first ovulation in prepubescent does
000132778 260__ $$c2024
000132778 5203_ $$aEarly exposure of does to sexually active bucks triggers early puberty onset correlating with neuroendocrine changes. However, the sensory pathways that are stimulated by the male are still unknown. Here, we assessed whether responses to olfactory stimuli are modulated by social experience (exposure to males or not) and/or endocrine status (prepubescent or pubescent). We used a calcium imaging approach on goat sensory cells from the main olfactory epithelium (MOE) and the vomeronasal organ (VNO). For both cell types, we observed robust responses to active male hair in females under three physiological conditions: prepubescent females isolated from males (ISOL PrePub), pubescent females exposed to males (INT Pub) and isolated females (ISOL Pub). Response analysis showed overall greater proportion of responses to buck hair in ISOL PrePub. We hypothesized that females would be more responsive to active buck hair during the prepubertal period, with numerous responses perhaps originating from immature neurons. We also observed a greater proportion of mature olfactory neurons in the MOE and VNO of INT Pub females suggesting that male exposure can induce plastic changes on olfactory cell function and organization. To determine whether stimulation by male odor can advance puberty, we exposed prepubescent does to active buck hair (ODOR). In both ODOR and females isolated from males (ISOL) groups, puberty was reached one month after females exposed to intact bucks (INT), suggesting that olfactory stimulation is not sufficient to trigger puberty.
000132778 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000132778 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000132778 700__ $$aPorte, Chantal
000132778 700__ $$aVacher, Hélène
000132778 700__ $$aTrives, Elliott
000132778 700__ $$aNakahara, Thiago S.
000132778 700__ $$aTrouillet, Anne-Charlotte
000132778 700__ $$0(orcid)0000-0003-2827-3054$$aAbecia, José A.$$uUniversidad de Zaragoza
000132778 700__ $$aDelgadillo, José A.
000132778 700__ $$aChemineau, Philippe
000132778 700__ $$aChamero, Pablo
000132778 700__ $$aKeller, Matthieu
000132778 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000132778 773__ $$g275 (2024), 114451 [11 pp.]$$pPhysiol. behav.$$tPhysiology and Behavior$$x0031-9384
000132778 8564_ $$s6270551$$uhttps://zaguan.unizar.es/record/132778/files/texto_completo.pdf$$yVersión publicada
000132778 8564_ $$s2477601$$uhttps://zaguan.unizar.es/record/132778/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000132778 909CO $$ooai:zaguan.unizar.es:132778$$particulos$$pdriver
000132778 951__ $$a2024-03-15-08:49:23
000132778 980__ $$aARTICLE