Routine results of an algorithm for managing the production of blood components
Pérez-Aliaga, Ana Isabel ; Ayerra, Irene ; Sánchez-Guillén, Javier ; López, F. Javier (Universidad de Zaragoza) ; Puente, Fernando ; Aranda, Alfonso ; Domingo, José María ; Garcés, Carmen
Resumen: Background and Objectives
The variability in the number of donations together with a growing demand for platelet concentrates and plasma‐derived medicines make us seek solutions aimed at optimizing the processing of blood. Some mathematical models to improve efficiencies in blood banking have been published. The goal of this work is to validate and evaluate an algorithm's impact in the production of blood components in the Blood and Tissues Bank of Aragon (BTBA).
Materials and Methods
A mathematical algorithm was designed, implemented and validated through simulations with real data. It was incorporated into the fractionation area, which uses the Reveos® fractionation system (Terumo BCT) to split blood into its components. After 9 months of daily routine validation, retrospective activity data from the Blood Bank and Transfusion Services before and during the use of the algorithm were compared.
Results
Using the algorithm, the outdating rate of platelet concentrates (PC) decreased by 87.8% in the blood bank. The average shelf life remaining of PC supplied to Transfusion Services increased by almost 1 day. As a consequence, the outdating rate in the Aragon Transfusion Network decreased by 33%. In addition, extra 100 litres of plasma were obtained in 9 months.
Conclusions
The algorithm improves the blood establishment's workflow and facilitates the decision‐making process in whole blood processing. It resulted in a decrease in PC outdating rate, increase in PC shelf life and finally an increase in the volume of recovered plasma, leading to significant cost savings.
Idioma: Inglés
DOI: 10.1111/vox.13609
Año: 2024
Publicado en: VOX SANGUINIS 119, 6 (2024), 541-547
ISSN: 0042-9007
Financiación: info:eu-repo/grantAgreement/ES/MICINN-AEI/PID2020-116873GB-I00
Financiación: info:eu-repo/grantAgreement/EUR/MICINN/TED2021-130702B-I00
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Área Estadís. Investig. Opera. (Dpto. Métodos Estadísticos)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. No puede utilizar el material para una finalidad comercial.
Exportado de SIDERAL (2024-07-11-08:52:28)
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The variability in the number of donations together with a growing demand for platelet concentrates and plasma‐derived medicines make us seek solutions aimed at optimizing the processing of blood. Some mathematical models to improve efficiencies in blood banking have been published. The goal of this work is to validate and evaluate an algorithm's impact in the production of blood components in the Blood and Tissues Bank of Aragon (BTBA).
Materials and Methods
A mathematical algorithm was designed, implemented and validated through simulations with real data. It was incorporated into the fractionation area, which uses the Reveos® fractionation system (Terumo BCT) to split blood into its components. After 9 months of daily routine validation, retrospective activity data from the Blood Bank and Transfusion Services before and during the use of the algorithm were compared.
Results
Using the algorithm, the outdating rate of platelet concentrates (PC) decreased by 87.8% in the blood bank. The average shelf life remaining of PC supplied to Transfusion Services increased by almost 1 day. As a consequence, the outdating rate in the Aragon Transfusion Network decreased by 33%. In addition, extra 100 litres of plasma were obtained in 9 months.
Conclusions
The algorithm improves the blood establishment's workflow and facilitates the decision‐making process in whole blood processing. It resulted in a decrease in PC outdating rate, increase in PC shelf life and finally an increase in the volume of recovered plasma, leading to significant cost savings.
Idioma: Inglés
DOI: 10.1111/vox.13609
Año: 2024
Publicado en: VOX SANGUINIS 119, 6 (2024), 541-547
ISSN: 0042-9007
Financiación: info:eu-repo/grantAgreement/ES/MICINN-AEI/PID2020-116873GB-I00
Financiación: info:eu-repo/grantAgreement/EUR/MICINN/TED2021-130702B-I00
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Área Estadís. Investig. Opera. (Dpto. Métodos Estadísticos)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. No puede utilizar el material para una finalidad comercial.Exportado de SIDERAL (2024-07-11-08:52:28)
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Artículos > Artículos por área > Estadística e Investigación Operativa
Registro creado el 2024-03-15, última modificación el 2024-07-11