000132883 001__ 132883
000132883 005__ 20250923084411.0
000132883 0247_ $$2doi$$a10.1016/j.yhbeh.2023.105474
000132883 0248_ $$2sideral$$a137759
000132883 037__ $$aART-2024-137759
000132883 041__ $$aeng
000132883 100__ $$aZapater-Fajarí, Mariola
000132883 245__ $$aHair cortisol and dehydroepiandrosterone and their associations with optimism and pessimism in older people
000132883 260__ $$c2024
000132883 5060_ $$aAccess copy available to the general public$$fUnrestricted
000132883 5203_ $$aThe cumulative negative effects of prolonged Hypothalamic-Pituitary-Adrenal axis (HPA axis) activation are associated with several age-related diseases. Some psychological traits such as optimism and pessimism have been shown to be related to both health and the stress response, although their relationship with the HPA axis is inconclusive. More stable HPA axis biomarkers, such as hair samples of cortisol (HC) and dehydroepiandrosterone (HDHEA), would help to clarify the association between these psychological traits and HPA axis functioning. The main aim of this study was to test the relationships between optimism and pessimism and chronic stress biomarkers measured in hair (HC and HDHEA). Additionally, a secondary objective was to explore sex differences in HC and HDHEA levels and their relationship with these psychological traits. We measured optimism, pessimism, and their combination (dispositional optimism) using the Life Orientation Test Revised (LOT-R) and chronic stress biomarkers (HC and HDHEA) in 119 healthy participants (46 men and 73 women) between 56 and 81 years old who belonged to a university program. Regression analyses controlling for perceived stress and BMI indicated that higher dispositional optimism was related to lower HC and HC:HDHEAratio (β = -0.256, p = .008 and β = -0.300, p = .002, respectively). More specifically, higher pessimism was related to higher HC (β = 0.235; p = .012) and HC:HDHEAratio (β = 0.240; p = .011), whereas higher optimism was associated with a lower HC:HDHEAratio(β = -0.205; p = .031). Moderation analyses showed no sex differences. To date, this is the first study to investigate the link between these traits and HC and HDHEA in older people. Our results confirm that positive and negative expectations about the future (i.e. optimism and pessimism) may play an important role in health due to their relationship with the HPA axis. They also strengthen the idea that the negative effects of pessimism have a greater weight than the protective effects of optimism in their relationship with HPA axis regulation.
000132883 536__ $$9info:eu-repo/grantAgreement/ES/MCIN/AEI/10.13039/501100011033$$9info:eu-repo/grantAgreement/ES/MEC/PSI2016-78763$$9info:eu-repo/grantAgreement/ES/MCIU/PSI2016-78763-P$$9info:eu-repo/grantAgreement/ES/MCIU/BES-2017-082148$$9info:eu-repo/grantAgreement/ES/DGA/S31-20D$$9Info:eu-repo/grantAgreement/ES/AEI/PID2020-119406GB-I00
000132883 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000132883 590__ $$a2.4$$b2024
000132883 592__ $$a0.822$$b2024
000132883 591__ $$aBEHAVIORAL SCIENCES$$b20 / 57 = 0.351$$c2024$$dQ2$$eT2
000132883 593__ $$aEndocrinology$$c2024$$dQ2
000132883 591__ $$aENDOCRINOLOGY & METABOLISM$$b124 / 191 = 0.649$$c2024$$dQ3$$eT2
000132883 593__ $$aBehavioral Neuroscience$$c2024$$dQ3
000132883 593__ $$aEndocrine and Autonomic Systems$$c2024$$dQ3
000132883 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000132883 700__ $$aCrespo-Sanmiguel, Isabel
000132883 700__ $$aMontoliu, Teresa
000132883 700__ $$0(orcid)0000-0003-3920-1099$$aHidalgo, Vanesa$$uUniversidad de Zaragoza
000132883 700__ $$aSalvador, Alicia
000132883 7102_ $$14009$$2725$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicobiología
000132883 773__ $$g159 (2024), 105474 [8 pp.]$$pHorm. behav.$$tHORMONES AND BEHAVIOR$$x0018-506X
000132883 8564_ $$s542421$$uhttps://zaguan.unizar.es/record/132883/files/texto_completo.pdf$$yVersión publicada
000132883 8564_ $$s2491192$$uhttps://zaguan.unizar.es/record/132883/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000132883 909CO $$ooai:zaguan.unizar.es:132883$$particulos$$pdriver
000132883 951__ $$a2025-09-22-14:30:07
000132883 980__ $$aARTICLE