000132888 001__ 132888
000132888 005__ 20250923084415.0
000132888 0247_ $$2doi$$a10.1016/j.cimid.2024.102151
000132888 0248_ $$2sideral$$a137764
000132888 037__ $$aART-2024-137764
000132888 041__ $$aeng
000132888 100__ $$0(orcid)0000-0001-5608-781X$$aMillán, Javier
000132888 245__ $$aHigh diversity, novel genotypes, and vertical transmission of hemotropic Mycoplasma in micromammals
000132888 260__ $$c2024
000132888 5060_ $$aAccess copy available to the general public$$fUnrestricted
000132888 5203_ $$aHemotropic mycoplasmas (hemoplasmas) are emerging zoonotic pathogens. Micromammals have received little attention as hosts for hemoplasmas despite their ubiquitous presence, high population abundances, and close association with humans. A PCR protocol targeting a fragment of the 16 S rRNA gene and direct sequencing in blood samples of 189 adult specimens and 35 fetuses belonging to three species of Eulipotyphla (shrews) and seven species of Rodentia, captured in three ecologically diverse habitats in North-Eastern Spain (Steppe, High Mountain, Mediterranean) yielded and occurrence of 26%, including 36% of 39 shrews and 23% of 150 rodents. Sequencing revealed the presence of 14 nucleotide sequence types (ntST) among the 56 readable sequences. In general, each ntST was associated with a given host species, although in some cases, the same ntST was sequenced in different species (chiefly rodents). Most ntST were closely related to rodent and/or bat hemoplasmas, but one was identical with Mycoplasma haemocanis/haemofelis, and others can be considered novel genotypes. High sequence diversity was detected in rodents, whereas in the white-toothed shrew (Crocidura russula), 9/11 sequences from two distant areas were identical. Phylogenetic and network analyses classified our sequences in different clades including hemoplasmas of rodents, carnivores, bats, and humans. Twelve of the fetuses (34.2%) of 9/12 litters (75.0%) of shrews and rodents were hemoplasma-positive, indicating frequent vertical transmission. Our study contributes to expanding our knowledge about the distribution, diversity, and transmission of hemoplasmas.
000132888 536__ $$9info:eu-repo/grantAgreement/ES/DGA/A16-23R$$9info:eu-repo/grantAgreement/ES/MICINN/CGL2010-17931
000132888 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000132888 590__ $$a2.0$$b2024
000132888 592__ $$a0.621$$b2024
000132888 591__ $$aVETERINARY SCIENCES$$b43 / 170 = 0.253$$c2024$$dQ2$$eT1
000132888 593__ $$aVeterinary (miscellaneous)$$c2024$$dQ1
000132888 591__ $$aMICROBIOLOGY$$b122 / 163 = 0.748$$c2024$$dQ3$$eT3
000132888 593__ $$aInfectious Diseases$$c2024$$dQ2
000132888 591__ $$aIMMUNOLOGY$$b143 / 183 = 0.781$$c2024$$dQ4$$eT3
000132888 593__ $$aMedicine (miscellaneous)$$c2024$$dQ2
000132888 593__ $$aMicrobiology$$c2024$$dQ3
000132888 593__ $$aImmunology$$c2024$$dQ3
000132888 593__ $$aImmunology and Allergy$$c2024$$dQ3
000132888 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000132888 700__ $$aMartín-Maldonado, Bárbara
000132888 700__ $$0(orcid)0000-0001-8435-6386$$aRodríguez-Pastor, Ruth$$uUniversidad de Zaragoza
000132888 700__ $$aMartínez-Padilla, Jesús
000132888 700__ $$aEsperón, Fernando
000132888 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000132888 773__ $$g107 (2024), 102151 [8 pp.]$$pComp. immunol. microbiol. infect. dis.$$tCOMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES$$x0147-9571
000132888 8564_ $$s3025100$$uhttps://zaguan.unizar.es/record/132888/files/texto_completo.pdf$$yVersión publicada
000132888 8564_ $$s2482128$$uhttps://zaguan.unizar.es/record/132888/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000132888 909CO $$ooai:zaguan.unizar.es:132888$$particulos$$pdriver
000132888 951__ $$a2025-09-22-14:32:12
000132888 980__ $$aARTICLE