000134595 001__ 134595
000134595 005__ 20240424142035.0
000134595 0247_ $$2doi$$a10.1515/jpem-2017-0024
000134595 0248_ $$2sideral$$a138232
000134595 037__ $$aART-2017-138232
000134595 041__ $$aeng
000134595 100__ $$0(orcid)0000-0001-8500-1667$$aMatute Llorente, Ángel$$uUniversidad de Zaragoza
000134595 245__ $$aPhysical activity and bone mineral density at the femoral neck subregions in adolescents with Down syndrome
000134595 260__ $$c2017
000134595 5060_ $$aAccess copy available to the general public$$fUnrestricted
000134595 5203_ $$aBackground:
Low bone mineral density (BMD) has been frequently described in subjects with Down syndrome (DS). Reduced physical activity (PA) levels may contribute to low BMD in this population. The objective of the study was to investigate whether PA levels were related to the femoral neck bone mass distribution in a sample of 14 males and 12 females with DS aged 12–18 years.

Methods:
BMD was evaluated by dual energy X-ray absorptiometry (DXA) at the integral, superolateral and inferomedial femoral neck regions and PA levels were assessed by accelerometry. The BMDs between the sexes and PA groups (below and above the 50th percentile of the total PA) were compared using independent t-tests and analyses of covariance (ANCOVAs) controlling for age, height and body weight.

Results:
No differences were found between the BMDs of males and females in any femoral neck region (p>0.05). Females with higher PA levels demonstrated increased integral (0.774 g/cm2 vs. 0.678 g/cm2) and superolateral femoral neck BMDs (0.696 g/cm2 vs. 0.595 g/cm2) compared to those with lower PA levels (p<0.05). In males, no differences (p<0.05) were found in the BMDs between the PA groups.

Conclusions:
This investigation shows that females accumulating more total PA presented increased BMDs at the integral and superolateral femoral neck regions (14.1% and 17.0%, respectively) when compared to their less active peers. These data highlight the importance of PA in females with DS to counteract their low bone mass and to improve their bone health.
000134595 536__ $$9info:eu-repo/grantAgreement/ES/MICINN/DEP2009-09183
000134595 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000134595 590__ $$a1.086$$b2017
000134595 591__ $$aPEDIATRICS$$b96 / 124 = 0.774$$c2017$$dQ4$$eT3
000134595 591__ $$aENDOCRINOLOGY & METABOLISM$$b130 / 141 = 0.922$$c2017$$dQ4$$eT3
000134595 592__ $$a0.465$$b2017
000134595 593__ $$aPediatrics, Perinatology and Child Health$$c2017$$dQ2
000134595 593__ $$aEndocrinology$$c2017$$dQ3
000134595 593__ $$aEndocrinology, Diabetes and Metabolism$$c2017$$dQ3
000134595 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000134595 700__ $$aGonzález Agüero, Alejandro
000134595 700__ $$0(orcid)0000-0002-4303-4097$$aVicente Rodríguez, Germán$$uUniversidad de Zaragoza
000134595 700__ $$aSardinha, Luis B
000134595 700__ $$aBaptista, Fatima
000134595 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús Mallén, José A$$uUniversidad de Zaragoza
000134595 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000134595 773__ $$g30, 10 (2017), 1075 - 1082$$pJ. pediatr. endocrinol. metab.$$tJournal of Pediatric Endocrinology and Metabolism$$x0334-018X
000134595 8564_ $$s184803$$uhttps://zaguan.unizar.es/record/134595/files/texto_completo.pdf$$yVersión publicada
000134595 8564_ $$s2899570$$uhttps://zaguan.unizar.es/record/134595/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000134595 909CO $$ooai:zaguan.unizar.es:134595$$particulos$$pdriver
000134595 951__ $$a2024-04-24-13:24:16
000134595 980__ $$aARTICLE