134595 20240424142035.0 doi 10.1515/jpem-2017-0024 sideral 138232 ART-2017-138232 eng Matute Llorente, Ángel Universidad de Zaragoza (orcid)0000-0001-8500-1667 Physical activity and bone mineral density at the femoral neck subregions in adolescents with Down syndrome 2017 Background: Low bone mineral density (BMD) has been frequently described in subjects with Down syndrome (DS). Reduced physical activity (PA) levels may contribute to low BMD in this population. The objective of the study was to investigate whether PA levels were related to the femoral neck bone mass distribution in a sample of 14 males and 12 females with DS aged 12–18 years. Methods: BMD was evaluated by dual energy X-ray absorptiometry (DXA) at the integral, superolateral and inferomedial femoral neck regions and PA levels were assessed by accelerometry. The BMDs between the sexes and PA groups (below and above the 50th percentile of the total PA) were compared using independent t-tests and analyses of covariance (ANCOVAs) controlling for age, height and body weight. Results: No differences were found between the BMDs of males and females in any femoral neck region (p>0.05). Females with higher PA levels demonstrated increased integral (0.774 g/cm2 vs. 0.678 g/cm2) and superolateral femoral neck BMDs (0.696 g/cm2 vs. 0.595 g/cm2) compared to those with lower PA levels (p<0.05). In males, no differences (p<0.05) were found in the BMDs between the PA groups. Conclusions: This investigation shows that females accumulating more total PA presented increased BMDs at the integral and superolateral femoral neck regions (14.1% and 17.0%, respectively) when compared to their less active peers. These data highlight the importance of PA in females with DS to counteract their low bone mass and to improve their bone health. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/MICINN/DEP2009-09183 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 1.086 2017 PEDIATRICS 96 / 124 = 0.774 2017 Q4 T3 ENDOCRINOLOGY & METABOLISM 130 / 141 = 0.922 2017 Q4 T3 0.465 2017 Pediatrics, Perinatology and Child Health 2017 Q2 Endocrinology 2017 Q3 Endocrinology, Diabetes and Metabolism 2017 Q3 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion González Agüero, Alejandro Vicente Rodríguez, Germán Universidad de Zaragoza (orcid)0000-0002-4303-4097 Sardinha, Luis B Baptista, Fatima Casajús Mallén, José A Universidad de Zaragoza (orcid)0000-0002-7215-6931 1006 245 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Educación Física y Depor. 30, 10 (2017), 1075 - 1082 J. pediatr. endocrinol. metab. Journal of Pediatric Endocrinology and Metabolism 0334-018X 184803 http://zaguan.unizar.es/record/134595/files/texto_completo.pdf Versión publicada 2899570 http://zaguan.unizar.es/record/134595/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:134595 articulos driver 2024-04-24-13:24:16 ARTICLE