000134632 001__ 134632
000134632 005__ 20240424142036.0
000134632 0247_ $$2doi$$a10.1016/j.jcpa.2024.03.207
000134632 0248_ $$2sideral$$a138304
000134632 037__ $$aART-2024-138304
000134632 041__ $$aeng
000134632 100__ $$aCalvo-Sánchez, Natalia
000134632 245__ $$aCorrugated intimal surface of the ovine aorta: when physiology resembles pathology
000134632 260__ $$c2024
000134632 5060_ $$aAccess copy available to the general public$$fUnrestricted
000134632 5203_ $$aThe aortic lumen in healthy animals is characterized by a smooth, whitish surface, but sheep have macroscopic corrugation of the intimal surface in the thoracic aorta (TA). Our aim was to determine if this finding was pathological or physiological. Thirteen sheep aortas were included in this work together with aortas from cattle (n = 3), a goat (n = 1), horses (n = 4), dogs (n = 2), rabbits (n = 2) and a pig (n = 1). A corrugated intimal surface in the TA was seen in all the sheep and the goat but was less evident in the cattle. Histologically, in sheep the TA intimal surface was seen to have multifocal bulging areas that protruded into the lumen. The outer half of the tunica media had numerous, randomly distributed muscle islands that disrupted the arrangement of the elastic lamella, displacing them towards the lumen. We conclude that the intimal corrugation of the TA in sheep is physiological and must not be misinterpreted as pathological.
000134632 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000134632 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000134632 700__ $$0(orcid)0000-0002-2685-1730$$aRodríguez-Largo, Ana
000134632 700__ $$aPuzol, Leonor
000134632 700__ $$ade Miguel, Ricardo
000134632 700__ $$aPérez, Estela$$uUniversidad de Zaragoza
000134632 700__ $$aGómez, Álex$$uUniversidad de Zaragoza
000134632 700__ $$aMicheloud, Juan F.
000134632 700__ $$0(orcid)0000-0002-2053-9842$$aLuján, Lluís$$uUniversidad de Zaragoza
000134632 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000134632 773__ $$g211 (2024), 8-11$$pJ. Comp. Pathol.$$tJOURNAL OF COMPARATIVE PATHOLOGY$$x0021-9975
000134632 8564_ $$s962923$$uhttps://zaguan.unizar.es/record/134632/files/texto_completo.pdf$$yVersión publicada
000134632 8564_ $$s2850819$$uhttps://zaguan.unizar.es/record/134632/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000134632 909CO $$ooai:zaguan.unizar.es:134632$$particulos$$pdriver
000134632 951__ $$a2024-04-24-13:24:58
000134632 980__ $$aARTICLE