134837 20260217205450.0 doi 10.1016/j.compbiomed.2024.108401 sideral 138346 ART-2024-138346 eng Heras-Sádaba, A. Universidad de Zaragoza Exploring the muscle architecture effect on the mechanical behaviour of mouse rotator cuff muscles 2024 Access copy available to the general public Unrestricted Incorporating detailed muscle architecture aspects into computational models can enable researchers to gain deeper insights into the complexity of muscle function, movement, and performance. In this study, we employed histological, multiphoton image processing, and finite element method techniques to characterise the mechanical dependency on the architectural behaviour of supraspinatus and infraspinatus mouse muscles. While mechanical tests revealed a stiffer passive behaviour in the supraspinatus muscle, the collagen content was found to be two times higher in the infraspinatus. This effect was unveiled by analysing the alignment of fibres during muscle stretch with the 3D models and the parameters obtained in the fitting. Therefore, a strong dependence of muscle behaviour, both active and passive, was found on fibre orientation rather than collagen content. info:eu-repo/grantAgreement/ES/DGA/T24-20R info:eu-repo/grantAgreement/ES/MICIU/PID2020-113822RB-C21 info:eu-repo/grantAgreement/ES/MICIU/PID2020-113822RB-C22 info:eu-repo/grantAgreement/ES/UZ/ICTS NANBIOSIS-U13 Unit-CIBER-BBN info:eu-repo/semantics/openAccess by-nc https://creativecommons.org/licenses/by-nc/4.0/deed.es 6.3 2024 BIOLOGY 7 / 107 = 0.065 2024 Q1 T1 MATHEMATICAL & COMPUTATIONAL BIOLOGY 4 / 67 = 0.06 2024 Q1 T1 ENGINEERING, BIOMEDICAL 22 / 124 = 0.177 2024 Q1 T1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS 26 / 177 = 0.147 2024 Q1 T1 1.447 2024 Health Informatics 2024 Q1 Computer Science Applications 2024 Q1 13.0 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pérez-Ruiz, A. Martins, P. Universidad de Zaragoza (orcid)0000-0001-9732-4498 Ederra, C. Ortiz de Solórzano, C. Abizanda, G. Pons-Villanueva, J. Calvo, B. Universidad de Zaragoza (orcid)0000-0001-9713-1813 Grasa, J. Universidad de Zaragoza (orcid)0000-0002-6870-0594 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 174 (2024), 108401 [12 pp.] Comput. biol. med. Computers in biology and medicine 0010-4825 5556312 http://zaguan.unizar.es/record/134837/files/texto_completo.pdf Versión publicada 2595533 http://zaguan.unizar.es/record/134837/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:134837 articulos driver 2026-02-17-20:18:56 ARTICLE