000135483 001__ 135483
000135483 005__ 20240529145159.0
000135483 0247_ $$2doi$$a10.35219/foodtechnology.2023.2.12
000135483 0248_ $$2sideral$$a138637
000135483 037__ $$aART-2024-138637
000135483 041__ $$aeng
000135483 100__ $$aDjaoudene, Ouarda
000135483 245__ $$aPhenolic compounds recovery from date seed and assessment of their antioxidant and enzyme inhibitory properties
000135483 260__ $$c2024
000135483 5060_ $$aAccess copy available to the general public$$fUnrestricted
000135483 5203_ $$aDate fruit is a highly important crop cultivated in arid and semi-arid regions, known for its nutritional value and health benefits. Dates' benefits extend beyond their edible portion and include seeds, which are a by-product of different industries, often considered waste, and have untapped potential. This work aimed to optimize the extraction conditions of antioxidant compounds from date seeds and assess their ability to inhibit disease-related enzymes. The optimization was carried out by examining the main parameters, including solvent type (acetone, ethanol, methanol, and water), solvent concentration (25–100%), sample-to-solvent ratio (10–60/20 mg/ml), and extraction time (15–90 min). Phenolic content (PC) was determined using the Folin-Ciocalteu method, while antioxidant activity was evaluated by ABTS and DPPH scavenging assays, as well as ferric reducing power (FRP). Based on the statistical analysis, 75% acetone, 10 mg/20 ml, and 45 min were found to be the best extraction conditions, manifesting a PC of 128.65 mg GAE/g dw, antiradical powers of 244.91 mg TE/g dw (ABTS) and 64.27 mg GAE/g dw (DPPH), and a FRP of 64.27 mg GAE/g dw. Moreover, the extract of date seed demonstrated a promising inhibitory property against some key enzymes such as tyrosinase, acetylcholinesterase, and α-glucosidase, which may be considered a good candidate for managing diabetes, Alzheimer's disease, and neurodegenerative disorders.
000135483 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000135483 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000135483 700__ $$aBachir-Bey, Mostapha
000135483 700__ $$aCásedas, Guillermo
000135483 700__ $$0(orcid)0000-0002-7972-7119$$aLes, Francisco
000135483 700__ $$aLópez, Víctor
000135483 773__ $$g47, 2 (2024), 190-206$$tAnnals of the University Dunarea de Jos of Galati, Fascicle VI: Food Technology$$x1843-5157
000135483 8564_ $$s932394$$uhttps://zaguan.unizar.es/record/135483/files/texto_completo.pdf$$yVersión publicada
000135483 8564_ $$s1780561$$uhttps://zaguan.unizar.es/record/135483/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000135483 909CO $$ooai:zaguan.unizar.es:135483$$particulos$$pdriver
000135483 951__ $$a2024-05-29-14:16:36
000135483 980__ $$aARTICLE