135506 20260217205602.0 doi 10.1007/s11920-024-01503-6 sideral 138656 ART-2024-138656 eng Alacreu-Crespo, Adrián Universidad de Zaragoza (orcid)0000-0002-0633-2810 From social stress and isolation to autonomic nervous system dysregulation in suicidal behavior 2024 Access copy available to the general public Unrestricted Purpose of Review: In this narrative review we wanted to describe the relationship of autonomic nervous system activity with social environment and suicidal spectrum behaviors. Recent Findings: Patients with suicidal ideation/suicide attempt have higher sympathetic nervous system (SNS) and lower parasympathetic nervous system (PNS) activity in resting conditions and during acute stress tasks compared with patients without suicidal ideation/suicide attempt. Death by suicide and violent suicide attempt also are related to SNS hyperactivation. Similarly, a SNS/PNS imbalance has been observed in people with childhood trauma, stressful life events or feelings of loneliness and isolation. Social support seems to increase PNS control and resilience. Summary: Due to the importance of the social context and stressful life events in suicidal behavior, SNS/PNS imbalance could act as a mediator in this relationship and be a source of relevant biomarkers. Childhood trauma and stressful life events may impair the autonomic nervous system response in suicidal patients. Loneliness, isolation and social support may act as moderators in acute stress situations. info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es 6.7 2024 PSYCHIATRY 18 / 288 = 0.062 2024 Q1 T1 PSYCHIATRY 18 / 288 = 0.062 2024 Q1 T1 2.37 2024 Psychiatry and Mental Health 2024 Q1 10.9 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Sebti, Emma Moret, Rosa María Courtet, Philippe 4009 680 Universidad de Zaragoza Dpto. Psicología y Sociología Área Person.Eval.Trat.Psicoló. 26 (2024), 312–322 Curr. Psychiatry Rep. CURRENT PSYCHIATRY REPORTS 1523-3812 949208 http://zaguan.unizar.es/record/135506/files/texto_completo.pdf Versión publicada 2310024 http://zaguan.unizar.es/record/135506/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:135506 articulos driver 2026-02-17-20:45:05 ARTICLE