135771 20260217205548.0 doi 10.1186/s13018-024-04785-x sideral 138773 ART-2024-138773 eng Enrique, Cordero García-Galán Biofilm on total joint replacement materials can be reduced through electromagnetic induction heating using a portable device 2024 Access copy available to the general public Unrestricted Background periprosthetic joint infection is a serious complication following joint replacement. The development of bacterial biofilms bestows antibiotic resistance and restricts treatment via implant retention surgery. Electromagnetic induction heating is a novel technique for antibacterial treatment of metallic surfaces that has demonstrated in-vitro efficacy. Previous studies have always employed stationary, non-portable devices. This study aims to assess the in-vitro efficacy of induction-heating disinfection of metallic surfaces using a new Portable Disinfection System based on Induction Heating. Methods Mature biofilms of three bacterial species: S. epidermidis ATCC 35,984, S. aureus ATCC 25,923, E. coli ATCC 25,922, were grown on 18 × 2 mm cylindrical coupons of Titanium-Aluminium-Vanadium (Ti6Al4V) or Cobalt-chromium-molybdenum (CoCrMo) alloys. Study intervention was induction-heating of the coupon surface up to 70ºC for 210s, performed using the Portable Disinfection System (PDSIH). Temperature was monitored using thermographic imaging. For each bacterial strain and each metallic alloy, experiments and controls were conducted in triplicate. Bacterial load was quantified through scraping and drop plate techniques. Data were evaluated using non-parametric Mann-Whitney U test for 2 group comparison. Statistical significance was fixed at p ≤ 0.05. Results All bacterial strains showed a statistically significant reduction of CFU per surface area in both materials. Bacterial load reduction amounted to 0.507 and 0.602 Log10 CFU/mL for S. aureus on Ti6Al4V and CoCrMo respectively, 5.937 and 3.500 Log10 CFU/mL for E. coli, and 1.222 and 0.372 Log10 CFU/mL for S. epidermidis. Conclusions Electromagnetic induction heating using PDSIH is efficacious to reduce mature biofilms of S aureus, E coli and S epidermidis growing on metallic surfaces of Ti6Al4V and CoCrMo alloys. info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es 2.8 2024 ORTHOPEDICS 30 / 140 = 0.214 2024 Q1 T1 0.877 2024 Surgery 2024 Q1 Orthopedics and Sports Medicine 2024 Q1 4.5 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Medel-Plaza, Marina Correa, John Jairo Aguilera Sarnago, Héctor Universidad de Zaragoza (orcid)0000-0001-8399-4650 Acero, Jesús Universidad de Zaragoza (orcid)0000-0001-7207-5536 Burdio, José M. Universidad de Zaragoza (orcid)0000-0002-9655-5531 Lucía, Óscar Universidad de Zaragoza (orcid)0000-0002-1284-9007 Esteban, Jaime Gómez-Barrena, Enrique 5008 785 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Tecnología Electrónica 19, 1 (2024), 304 [7 pp.] Journal of orthopaedic surgery and research Journal of Orthopaedic Surgery and Research 1749-799X 1382204 http://zaguan.unizar.es/record/135771/files/texto_completo.pdf Versión publicada 2280864 http://zaguan.unizar.es/record/135771/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:135771 articulos driver 2026-02-17-20:39:03 ARTICLE